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Relationship between airway obstruction and incidence of metabolic syndrome in Korea: a community-based cohort study

Authors
 Kim CY  ;  Park Y  ;  Leem AY  ;  Chung KS  ;  Jung JY  ;  Park MS  ;  Kim YS 
Citation
 INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, Vol.13 : 2057-2063, 2018 
Journal Title
 INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE 
ISSN
 1176-9106 
Issue Date
2018
Keywords
COPD ; incidence ; metabolic syndrome
Abstract
Background: Although studies have examined the relationship between metabolic syndrome (MetS) and COPD, the incidence of MetS in individuals with COPD has not specifically been investigated. This study aimed to evaluate the incidence of MetS in subjects with airway obstruction using data from a community-based cohort. Patients and methods: Data representing 4 years of follow-up from the Ansung-Ansan cohort were analyzed; a total of 6,184 adults, who were ≥40 years of age and underwent spirometry, were enrolled in this study. Airway obstruction was defined as forced expiratory volume in 1 s/forced vital capacity ratio <70%, and MetS was determined according to the National Cholesterol Education Program Adult Treatment Panel III guidelines. Results: A total of 419 patients were newly diagnosed with MetS, based on the National Cholesterol Education Program Adult Treatment Panel III guidelines, during follow-up. MetS was more frequent in COPD subjects, relative to non-COPD subjects, in both sexes (14.7% vs 11.0% [men] and 14.7% vs 11.8% [women]). In men subjects, the risk for MetS was higher in subjects with airflow obstruction than in subjects without obstruction, after adjusting for age, body mass index, and smoking status. Conclusion: The incidence of MetS was higher in men with airflow obstruction than in healthy subjects.
Files in This Item:
T201802215.pdf Download
DOI
10.2147/COPD.S157453
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Sam(김영삼) ORCID logo https://orcid.org/0000-0001-9656-8482
Kim, Chi Young(김치영)
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Leem, Ah Young(임아영) ORCID logo https://orcid.org/0000-0001-5165-3704
Jung, Kyung Soo(정경수) ORCID logo https://orcid.org/0000-0003-1604-8730
Jung, Ji Ye(정지예) ORCID logo https://orcid.org/0000-0003-1589-4142
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163140
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