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Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

Authors
 Ju Yeong Kim  ;  Tai-Soon Yong  ;  Han-Jong Rim  ;  Jong-Yil Chai  ;  Duk-Young Min  ;  Keeseon S Eom  ;  Woon-Mok Sohn  ;  Jae Hoon Lim  ;  Dongil Choi  ;  Sithat Insisiengmay  ;  Bounlay Phommasack  ;  Bounnaloth Insisiengmay 
Citation
 Acta Tropica, Vol.182 : 128-134, 2018 
Journal Title
 Acta Tropica 
ISSN
 0001-706X 
Issue Date
2018
Keywords
Abdominal ultrasonography ; Cholangiocarcinoma ; Lao PDR ; Opisthorchiasis ; Opisthorchis viverrini ; Stool ova examination
Abstract
Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade>/=2) was also significantly more prevalent (P<0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.
Full Text
https://www.sciencedirect.com/science/article/pii/S0001706X17303121
DOI
10.1016/j.actatropica.2018.02.031
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Environmental Medical Biology (환경의생물학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ju Young(김주영) ORCID logo https://orcid.org/0000-0003-2456-6298
Yong, Tai Soon(용태순) ORCID logo https://orcid.org/0000-0002-3445-0769
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/162591
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