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Brain abscess caused by chronic invasive actinomycosis in the nasopharynx: A case report and literature review

 Chi Sang Hwang  ;  Haneul Lee  ;  Min Pyo Hong  ;  Ji Hyung Kim  ;  Kyung-Su Kim 
 MEDICINE, Vol.97(16) : e0406, 2018 
Journal Title
Issue Date
Actinomycosis/diagnostic imaging/*microbiology/therapy ; Anti-Bacterial Agents/therapeutic use ; Brain Abscess/diagnostic imaging/*microbiology/therapy ; Chronic Disease ; Drainage ; Female ; Humans ; Middle Aged ; Nasopharyngeal Diseases/drug therapy/*microbiology ; Recurrence ; X-Ray Computed Tomography
RATIONALE: Actinomycosis is a rare anaerobic, gram-positive bacterial infection caused by Actinomyces, which is part of the normal flora in the oral cavity and respiratory and female genitourinary tracts. The cervicofacial area is the most common site of involvement, and involvement of the central nervous system is rare. PATIENT CONCERNS: We report a case involving a 51-year-old woman who developed an actinomycotic brain abscess 15 months after the treatment of noninvasive nasopharyngeal actinomycosis, which recurred as an invasive form. DIAGNOSES: Histopathological examination of the surgical specimens revealed actinomycosis. INTERVENTIONS: The patient was treated by surgical drainage of the brain abscess and long-term antibiotic treatment. OUTCOMES: Follow-up brain imaging performed 12 months after surgery showed complete resolution of the brain abscess, and there were no further signs or symptoms of infection. LESSONS: Physicians should be aware of the typical clinical presentations of cervicofacial actinomycosis. Moreover, they should know that actinomycosis may mimic the process of malignancy at various anatomical locations.
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1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Su(김경수) ORCID logo https://orcid.org/0000-0003-1460-0640
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