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Heart Rate Recovery and Cancer Risk: Prospective Cohort Study

Authors
 Yong Hyun Byun  ;  Sang Yeun Kim  ;  Yejin Mok  ;  Youngwon Kim  ;  Sun Ha Jee 
Citation
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH, Vol.30(1) : 45-55, 2018 
Journal Title
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH 
ISSN
 1010-5395 
Issue Date
2018
Keywords
cancer ; cohort study ; exercise treadmill test ; heart rate recovery
Abstract
This study aims to determine the association between 2-minute heart rate recovery (HRR) and cancer risk. Each participant (5379 women; 8485 men) provided HRR obtained from treadmill tests. The outcome was site-specific cancer. Over 9 years of follow-up, 630 cancer events (258 women) were accrued. Slower HRR was associated with increased thyroid cancer risk in women ( P for trend = .0121) and colorectal cancer risk in men ( P for trend = .0034). The lowest HRR (<13 bpm) had higher hazards of thyroid cancer (hazard ratio [HR] = 2.20; 95% CI = 1.28-3.77) in women and colorectal cancer (HR = 3.08; 95% CI = 1.32-7.15) in men. In women, slower HRR and lower proportions of heart rate recovery (PHRR) were associated with higher hazards of thyroid cancer in women and metabolically related cancers (liver and colorectal) in men. Slower HRR and lower PHRR were independent risk factors for thyroid cancer in women and metabolically related cancers in men.
Full Text
http://journals.sagepub.com/doi/10.1177/1010539517745630
DOI
10.1177/1010539517745630
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/162295
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