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Cardiac Metastasis from Clivus Chordoma

Authors
 Jun Won Kim  ;  Chang-Ki Hong  ;  Yoon Jin Cha  ;  Se Hoon Kim  ;  Chang-Ok Suh  ;  Kyu-Sung Lee 
Citation
 World Neurosurgery, Vol.113 : 103-107, 2018 
Journal Title
 World Neurosurgery 
ISSN
 1878-8750 
Issue Date
2018
MeSH
Adult ; Brain Neoplasms/diagnostic imaging/*pathology ; Chordoma/diagnostic imaging/*pathology ; Posterior Cranial Fossa ; Female ; Heart Neoplasms/diagnostic imaging/*secondary ; Humans ; Skull Base Neoplasms/diagnostic imaging/*pathology
Keywords
Adjuvant IMRT ; Cardiac metastasis ; Case report ; Clivus chordoma ; Total resection
Abstract
BACKGROUND: Chordomas are rare tumors showing locally aggressive nature and high rates of local recurrences. Distant metastases are infrequently reported and cardiac metastases are extremely rare. CASE DESCRIPTION: A 32-year-old woman had been diagnosed with a large chordoma involving the clivus. She received a total removal of the tumor and adjuvant intensity-modulated radiotherapy. Four and a half years after the surgery, she presented with multifocal lesions in the ventricles and the right atrium, although an open thoracotomy revealed chronic inflammation. Two years after finding the cardiac lesions, thoracoscopic biopsy of the chest wall lesion revealed metastatic chordoma. She received palliative imatinib for 2 weeks before she died of tumor progression. CONCLUSION: This case illustrates the metastatic potential of clivus chordoma, and the heart can be a site of metastasis.
Full Text
https://www.sciencedirect.com/science/article/pii/S1878875018303115
DOI
10.1016/j.wneu.2018.02.041
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
김세훈(Kim, Se Hoon) ORCID logo https://orcid.org/0000-0001-7516-7372
김준원(Kim, Jun Won) ORCID logo https://orcid.org/0000-0003-1358-364X
서창옥(Suh, Chang Ok)
이규성(Lee, Kyu Sung)
차윤진(Cha, Yoon Jin) ORCID logo https://orcid.org/0000-0002-5967-4064
홍창기(Hong, Chang Ki)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/162279
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