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Five-Year Follow-Up and Outcomes of Noninvasive Ventilation in Subjects With Neuromuscular Diseases

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dc.contributor.author강성웅-
dc.contributor.author김은영-
dc.contributor.author서미리-
dc.contributor.author최원아-
dc.date.accessioned2018-08-28T16:56:23Z-
dc.date.available2018-08-28T16:56:23Z-
dc.date.issued2018-
dc.identifier.issn0020-1324-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/162088-
dc.description.abstractINTRODUCTION: The purpose of this study was to investigate the 5-year outcomes of noninvasive ventilation (NIV) application in different neuromuscular disease (NMD) groups. METHODS: We categorized 180 subjects who had initiated NIV between March 2001 and August 2009 into 4 groups and followed them for > 5 y. The NIV maintenance rate and average duration, applying time, and forced vital capacity (FVC) were investigated at the time NIV was initiated and 5 y after NIV initiation in each group. RESULTS: In subjects with amyotrophic lateral sclerosis (ALS), Duchenne muscular dystrophy (DMD), and spinal muscular atrophy (SMA)-congenital myopathy, the 5-year subjects who continued to use NIV over time were 22.5%, 89.4%, and 91.3%, respectively, and the average NIV maintenance durations were 21.53 ± 19.26 months, 55.22 ± 11.47 months, and 57.48 ± 8.34 months, respectively (P < .001). Median daily applying time changed from 8.0 h to 24.0 h (P < .001), from 8.0 h to 12.0 h (P < .001), and from 8.0 h to 9.0 h (P = .11) in subjects with ALS, DMD, and SMA-congenital myopathy, respectively. FVC decreased significantly after 5 y except in the group with combined SMA-congenital myopathy. CONCLUSIONS: NIV was tolerated long-term without significant increases in daily application time for most subjects with NMD. However, in individuals with ALS, development of severe bulbar symptoms can risk maintaining NIV.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherDaedalus Enterprises for the American Association for Respiratory Therapy-
dc.relation.isPartOfRESPIRATORY CARE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleFive-Year Follow-Up and Outcomes of Noninvasive Ventilation in Subjects With Neuromuscular Diseases-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Rehabilitation Medicine-
dc.contributor.googleauthorMi Ri Suh-
dc.contributor.googleauthorWon Ah Choi-
dc.contributor.googleauthorDong Hyun Kim-
dc.contributor.googleauthorJang Woo Lee-
dc.contributor.googleauthorEun Young Kim-
dc.contributor.googleauthorSeong-Woong Kang-
dc.identifier.doi10.4187/respcare.05475-
dc.contributor.localIdA00041-
dc.contributor.localIdA05462-
dc.contributor.localIdA04582-
dc.contributor.localIdA04125-
dc.relation.journalcodeJ02614-
dc.identifier.eissn1943-3654-
dc.identifier.pmid29298901-
dc.identifier.urlhttp://rc.rcjournal.com/content/63/3/274-
dc.subject.keywordamyotrophic lateral sclerosis-
dc.subject.keywordcongenital myopathy-
dc.subject.keywordduchenne muscular dystrophy-
dc.subject.keywordneuromuscular disease-
dc.subject.keywordnoninvasive ventilation-
dc.subject.keywordspinal muscular atrophy-
dc.contributor.alternativeNameKang, Seong Woong-
dc.contributor.alternativeNameKim, Eun Young-
dc.contributor.alternativeNameSuh, Mi Ri-
dc.contributor.alternativeNameChoi, Won Ah-
dc.contributor.affiliatedAuthorKang, Seong Woong-
dc.contributor.affiliatedAuthorKim, Eun Young-
dc.contributor.affiliatedAuthorSuh, Mi Ri-
dc.contributor.affiliatedAuthorChoi, Won Ah-
dc.citation.volume63-
dc.citation.number3-
dc.citation.startPage274-
dc.citation.endPage281-
dc.identifier.bibliographicCitationRESPIRATORY CARE, Vol.63(3) : 274-281, 2018-
dc.identifier.rimsid59678-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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