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Does Botulinum Toxin Injection into Masseter Muscles Affect Subcutaneous Thickness?

Authors
 Gunwoo Park  ;  Young-Chan Choi  ;  Jung-Hee Bae  ;  Seong-Taek Kim 
Citation
 Aesthetic Suregry Journal, Vol.38(2) : 192-198, 2018 
Journal Title
 Aesthetic Suregry Journal 
ISSN
 1090-820X 
Issue Date
2018
Abstract
Background: Botulinum toxin (BoNT) is widely used to treat masseter muscle hypertrophy. Changes in the muscle thickness have been found in many studies, but there has been no report on changes in the thickness from the skin surface to the masseter muscle. Objectives: We aimed to use ultrasonography to measure not only changes in the muscle thickness but also changes in subcutaneous thickness. Methods: This study enrolled 20 volunteer patients: 10 were assigned to an experimental group (injected with each side 25 U of botulinum toxin into both masseter muscles) and 10 to a control group (injected with normal saline). The thicknesses were measured before the injection and at 4, 8, and 12 weeks after the injection both at rest and during maximum muscle contraction. Results: The subcutaneous thickness did not differ significantly over time either at rest (P = 0.063) or during maximal contraction (P = 0.392), or between the experimental and control groups at rest (P = 0.392) or during maximum contraction (P = 0.259). The muscle thickness in the experimental group differed significantly over time. Conclusions: Botulinum toxin injection only changes the muscle thickness and does not affect the subcutaneous thickness from the skin surface to the masseter muscle.
Full Text
https://academic.oup.com/asj/article/38/2/192/3883685
DOI
10.1093/asj/sjx102
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers
Yonsei Authors
김성택(Kim, Seong Taek)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161983
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