Cited 6 times in
Protective effects of biodegradable collagen implants on thinned sclera after strabismus surgery: a paired-eye study
DC Field | Value | Language |
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dc.contributor.author | 한승한 | - |
dc.contributor.author | 한진우 | - |
dc.date.accessioned | 2018-07-20T12:00:14Z | - |
dc.date.available | 2018-07-20T12:00:14Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1091-8531 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161622 | - |
dc.description.abstract | PURPOSE: To determine the efficacy of a biodegradable Ologen (Aeon Astron Europe BV, Leiden, The Netherlands) collagen matrix in reducing the blue color change due to exposed thinned sclera after strabismus surgery. METHODS: Fourteen patients with intermittent exotropia undergoing symmetric bilateral lateral rectus recession surgery were included in this prospective, randomized, paired-eye controlled study. In each patient, Ologen was implanted at the original rectus insertion site in one randomly selected eye; the other eye underwent conventional surgery. Ologen was inserted under the conjunctiva without suturing, covering the muscle insertion site. Conjunctival color change was analyzed using computer-based image analysis immediately and 1 week, 1 month, and 3 months postoperatively. Slit-lamp photographs of each eye were evaluated using contrast limited adaptive histogram equalization (CLAHE), Canny edge, and the RGB (red-green-blue) model. Secondary outcomes were conjunctival and sclera thickness 3 months postoperatively determined by anterior segment optical coherence tomography. RESULTS: Immediately and 1 week postoperatively all color models showed no significant differences between Ologen-implanted and control eyes. Three months postoperatively, Ologen-implanted eyes exhibited significantly lower CLAHE (P = 0.041) and RGB model blue color (P = 0.008) values than control eyes. Canny edge (P = 0.061) and RGB model red color (P = 0.152) values did not differ between eyes. Conjunctival stroma and episcleral complex thickness was greater in Ologen-implanted eyes than in controls (P = 0.001). CONCLUSIONS: Blue color change was significantly less noticeable in Ologen-implanted eyes than in controls. Thus, Ologen implantation helps prevent visible blue sclera at the original rectus insertion site after lateral rectus recession. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mosby | - |
dc.relation.isPartOf | JOURNAL OF AAPOS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Protective effects of biodegradable collagen implants on thinned sclera after strabismus surgery: a paired-eye study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Ophthalmology | - |
dc.contributor.googleauthor | Tae Keun Yoo | - |
dc.contributor.googleauthor | Sueng-Han Han | - |
dc.contributor.googleauthor | Jinu Han | - |
dc.identifier.doi | 10.1016/j.jaapos.2017.07.217 | - |
dc.contributor.localId | A04303 | - |
dc.contributor.localId | A04329 | - |
dc.relation.journalcode | J01219 | - |
dc.identifier.eissn | 1528-3933 | - |
dc.identifier.pmid | 29102674 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1091853117302276?via%3Dihub | - |
dc.contributor.alternativeName | Han, Seung Han | - |
dc.contributor.alternativeName | Han, Jin U | - |
dc.contributor.affiliatedAuthor | Han, Seung Han | - |
dc.contributor.affiliatedAuthor | Han, Jin U | - |
dc.citation.volume | 21 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 467 | - |
dc.citation.endPage | 471.e1. | - |
dc.identifier.bibliographicCitation | JOURNAL OF AAPOS, Vol.21(6) : 467-471.e1., 2017 | - |
dc.identifier.rimsid | 61645 | - |
dc.type.rims | ART | - |
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