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Consensus on Stereotactic Body Radiation Therapy for Small-Sized Hepatocellular Carcinoma at the 7th Asia-Pacific Primary Liver Cancer Expert Meeting

Authors
 Zhao-Chong Zeng  ;  Jinsil Seong  ;  Sang Min Yoon  ;  Jason Chia-Hsien Cheng  ;  Ka-On Lam  ;  Ann-Shing Lee  ;  Ada Law  ;  Jian-Ying Zhang  ;  Yong Hu 
Citation
 LIVER CANCER, Vol.6(4) : 264-274, 2017 
Journal Title
LIVER CANCER
ISSN
 2235-1795 
Issue Date
2017
Keywords
Hepatocellular carcinoma ; Radiation-induced liver disease ; Stereotactic body radiation therapy ; Survival
Abstract
Background: Stereotactic body radiation therapy (SBRT) is an advanced technique of external beam radiation therapy that delivers large ablative doses of radiation. In the past decade, many cancer centers have adopted SBRT as one mode of radically treating small-sized hepatocellular carcinoma (HCC), based on encouraging clinical outcomes. SBRT thus seems reasonable as first-line treatment of inoperable HCC confined to the liver. However, most of the clinical studies to date have been retrospective in nature, with key issues still under investigation. Summary: The above-mentioned publications were subjected to scrutiny, fueling discussions at the 7th Asia-Pacific Primary Liver Cancer Expert (APPLE 2016) Meeting on various clinical variables, such as indications for SBRT, therapeutic outcomes, treatment-related toxicities, doses prescribed, and specific techniques. The consensus reached should be of interest to all professionals active in the treatment of HCC, especially radiation oncologists. Key Messages: SBRT is a safe and effective therapeutic option for patients with small-sized HCC, offering substantial local control, improved overall survival, and low toxicity.
Files in This Item:
T201704790.pdf Download
DOI
10.1159/000475768
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Seong, Jin Sil(성진실) ORCID logo https://orcid.org/0000-0003-1794-5951
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161434
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