Cited 35 times in
Vascular and metabolic comorbidities in open-angle glaucoma with low- and high-teen intraocular pressure: a cross-sectional study from South Korea
DC Field | Value | Language |
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dc.contributor.author | 김규아 | - |
dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 배형원 | - |
dc.contributor.author | 성공제 | - |
dc.contributor.author | 이시형 | - |
dc.contributor.author | 이원석 | - |
dc.date.accessioned | 2018-07-20T08:47:39Z | - |
dc.date.available | 2018-07-20T08:47:39Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1755-375X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161397 | - |
dc.description.abstract | PURPOSE: To assess the associations between vascular and metabolic comorbidities and the prevalence of open-angle glaucoma (OAG) with low-teen and high-teen intraocular pressure (IOP) in Korea. METHODS: Cross-sectional data from the Korean National Health and Nutrition Examination Survey from 2008 to 2012 were analysed. Participants diagnosed with OAG with normal IOP were further classified into low-teen IOP (IOP ≤ 15 mmHg) and high-teen IOP (15 mmHg < IOP ≤ 21 mmHg) groups. Using multiple logistic regression analyses, the associations between vascular and metabolic comorbidities and the prevalence of glaucoma were investigated for the low- and high-teen IOP groups. RESULTS: The prevalences of hypertension, hyperlipidemia, ischaemic heart disease, stroke and metabolic syndrome were significantly higher among subjects with low-teen OAG compared with normal subjects, while only the prevalences of hypertension and stroke were higher among subjects with high-teen OAG compared with normal subjects. In multivariate logistic regression models adjusted for confounding factors, low-teen OAG was significantly associated with hypertension (OR, 1.68; 95% CI, 1.30-2.18), hyperlipidemia (OR, 1.49; 95% CI, 1.07-2.08), ischaemic heart disease (OR, 1.83; 95% CI, 1.07-3.11), stroke (OR, 1.91; 95% CI, 1.12-3.25) and metabolic syndrome (OR, 1.46; 95% CI, 1.12-1.90). High-teen OAG was only associated with stroke (OR, 2.58; 95% CI, 1.20-5.53). CONCLUSION: Various vascular and metabolic comorbidities were significantly associated with low-teen OAG, but not with high-teen OAG. These data support the hypothesis that vascular factors play a more significant role in the pathogenesis of OAG with low-teen baseline IOP. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Munksgaard | - |
dc.relation.isPartOf | ACTA OPHTHALMOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Comorbidity | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glaucoma, Open-Angle/epidemiology* | - |
dc.subject.MESH | Glaucoma, Open-Angle/physiopathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperlipidemias/epidemiology* | - |
dc.subject.MESH | Hypertension/epidemiology* | - |
dc.subject.MESH | Intraocular Pressure/physiology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nutrition Surveys* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Vascular and metabolic comorbidities in open-angle glaucoma with low- and high-teen intraocular pressure: a cross-sectional study from South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Ophthalmology | - |
dc.contributor.googleauthor | Si Hyung Lee | - |
dc.contributor.googleauthor | Gyu Ah Kim | - |
dc.contributor.googleauthor | Wonseok Lee | - |
dc.contributor.googleauthor | Hyoung Won Bae | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Chan Yun Kim | - |
dc.identifier.doi | 10.1111/aos.13487 | - |
dc.contributor.localId | A00326 | - |
dc.contributor.localId | A01035 | - |
dc.contributor.localId | A01814 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A04630 | - |
dc.contributor.localId | A05378 | - |
dc.relation.journalcode | J00025 | - |
dc.identifier.eissn | 1755-3768 | - |
dc.identifier.pmid | 28677865 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.13487 | - |
dc.subject.keyword | diabetes | - |
dc.subject.keyword | hyperlipidemia | - |
dc.subject.keyword | hypertension | - |
dc.subject.keyword | metabolic syndrome | - |
dc.subject.keyword | normal-tension glaucoma | - |
dc.contributor.alternativeName | Kim, Gyuah | - |
dc.contributor.alternativeName | Kim, Chan Yun | - |
dc.contributor.alternativeName | Bae, Hyoung Won | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.alternativeName | Lee, Si Hyung | - |
dc.contributor.alternativeName | Lee, Wonseok | - |
dc.contributor.affiliatedAuthor | Kim, Gyuah | - |
dc.contributor.affiliatedAuthor | Kim, Chan Yun | - |
dc.contributor.affiliatedAuthor | Bae, Hyoung Won | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Lee, Si Hyung | - |
dc.contributor.affiliatedAuthor | Lee, Wonseok | - |
dc.citation.volume | 95 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | e564 | - |
dc.citation.endPage | e574 | - |
dc.identifier.bibliographicCitation | ACTA OPHTHALMOLOGICA, Vol.95(7) : e564-e574, 2017 | - |
dc.identifier.rimsid | 61315 | - |
dc.type.rims | ART | - |
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