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Palliative radiation therapy in the last 30 days of life: A systematic review

Authors
 Kyung Ran Park  ;  Chang Geol Lee  ;  Yolanda D. Tseng  ;  Jay J. Liao  ;  Suresh Reddy  ;  Eduardo Bruera  ;  Sriram Yennurajalingam 
Citation
 Radiotherapy and Oncology, Vol.125(2) : 193-199, 2017 
Journal Title
 Radiotherapy and Oncology 
ISSN
 0167-8140 
Issue Date
2017
MeSH
Databases, Factual ; Humans ; Neoplasms/mortality ; Neoplasms/radiotherapy* ; Palliative Care/methods ; Palliative Care/utilization* ; Radiotherapy/utilization* ; Terminal Care/methods ; Terminal Care/utilization*
Keywords
End-of-life ; Last 30 days of life ; Palliative radiation therapy ; Systematic review
Abstract
PURPOSE: To investigate the utilization of palliative radiation therapy (RT), predictors for the use of RT, and symptom palliation following RT during the last 30 days of life through systemic review of literature. MATERIALS/METHODS: A systematic search of available medical literature databases was performed on patients receiving palliative RT in the last 30 days of life. A total of 18 studies were evaluated. RESULTS: The overall palliative RT utilization rates during the last month of life were in the range of 5-10% among patients who died of cancer and 9-15.3% of patients who received palliative RT. The most commonly used regimen was 30 Gy in 10 fractions (36-90%). Single fraction RT utilization ranged from 0% to 59%. ECOG performance status 3-4 was significantly associated with patients receiving RT in the last 30 days of life and shorter survival. Twenty-six percent of patients who survived less than 1 month were reported to show symptom palliation following RT. CONCLUSION: Palliative RT was performed in approximately 10% of patients who died of cancer near their end of life, with the most commonly used regimen of 30 Gy in 10 fractions. This study suggests that greater use of shorter or single fraction regimens may be beneficial, especially in patients with poor performance status.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161369
DOI
10.1016/j.radonc.2017.09.016
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실)
Yonsei Authors
이창걸(Lee, Chang Geol)
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Full Text
https://www.sciencedirect.com/science/article/pii/S0167814017325835
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