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Vitamin D deficiency adversely affects early post-operative functional outcomes after total knee arthroplasty

Authors
 Keun-Young Shin  ;  Kwan Kyu Park  ;  Seong-Hwan Moon  ;  Ick Hwan Yang  ;  Ho-June Choi  ;  Woo-Suk Lee 
Citation
 KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, Vol.25(11) : 3424-3430, 2017 
Journal Title
 KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY 
ISSN
 0942-2056 
Issue Date
2017
MeSH
Aged ; Arthroplasty, Replacement, Knee/rehabilitation* ; Female ; Humans ; Knee/surgery ; Male ; Middle Aged ; Osteoarthritis, Knee/blood ; Osteoarthritis, Knee/complications ; Osteoarthritis, Knee/surgery* ; Postoperative Period ; Prospective Studies ; Recovery of Function ; Time Factors ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/complications*
Keywords
American Knee Society Score ; Functional outcomes ; Performance tests ; Total knee arthroplasty ; Vitamin D
Abstract
PURPOSE: Vitamin D has received considerable attention in recent years owing to the increasing evidence of its importance in muscle function and physical performance. The present study attempted to determine whether patients with low serum vitamin D levels had impairment in early functional outcomes following total knee arthroplasty (TKA). METHODS: This was a prospective cohort study that included 92 patients. Patients were divided into two groups according to their vitamin D levels as assessed at the preoperative visit: (1) vitamin D-deficient group, serum 25-hydroxyvitamin D3 (25(OH)D) levels <12 ng/mL; (2) vitamin D non-deficient group, serum 25(OH)D levels ≥12 ng/mL. American Knee Society Score (KSS) and four other performance tests including the alternative step test (AST), six-metre walk test (SMT), sit-to-stand test (STS), and timed up and go test (TUGT) were used for assessment of post-operative function. All assessments were performed one day before and three months after TKA. RESULTS: Of the 92 patients included in the study, 87 patients performed all required assessments. The mean post-operative functional KSS was significantly lesser in the vitamin D-deficient group than in the vitamin D non-deficient group (67.2 vs. 73.4, p = 0.031). The mean values of time taken for post-operative AST (16.6 vs. 14.6 s, p = 0.033) and SMT (8.8 vs. 7.7 s, p = 0.012) were significantly longer in the vitamin D-deficient group than in the vitamin D non-deficient group. Post-operative STS and TUGT demonstrated higher values for mean time taken in the vitamin D-deficient group than in the vitamin D non-deficient group, but these were not statistically significant (13.6 vs. 12.4 s, not significant (n.s.); 12.7 vs. 11.7 s, n.s., respectively). CONCLUSION: Early post-operative functional outcomes following TKA appear to be adversely affected by vitamin D deficiency. LEVEL OF EVIDENCE: Prospective cohort study, Level II.
Full Text
https://link.springer.com/article/10.1007%2Fs00167-016-4209-8
DOI
10.1007/s00167-016-4209-8
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Seong Hwan(문성환)
Park, Kwan Kyu(박관규) ORCID logo https://orcid.org/0000-0003-0514-3257
Shin, Keun-Young(신근영)
Yang, Ick Hwan(양익환)
Lee, Woo Suk(이우석) ORCID logo https://orcid.org/0000-0002-0798-1660
Choi, Ho June(최호준)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161272
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