17 15

Cited 0 times in

Clinical Significance of Periurethral Calcification According to the Location in Men With Lower Urinary Tract Symptoms and a Small Prostate Volume

Authors
 Jang Hee Han  ;  Joo Yong Lee  ;  Jong Kyu Kwon  ;  Jong Soo Lee  ;  Kang Su Cho 
Citation
 International Neurourology Journal (대한배뇨장애요실금학회지), Vol.21(3) : 220-228, 2017 
Journal Title
 International Neurourology Journal (대한배뇨장애요실금학회지) 
ISSN
 2093-4777 
Issue Date
2017
Keywords
Calculi ; Inflammation ; Lower urinary tract symptoms ; Prostatic hyperplasia ; Urethra
Abstract
PURPOSE: To assess the impact of periurethral calcification (PUC) according to its location on uroflowmetric parameters and urinary symptoms in patients with small prostate volume (PV). METHODS: Records were obtained from a prospectively maintained database of first-visit men with lower urinary tract symptoms (LUTS). Patients whose PV was >30 mL were excluded to elucidate more clearly the impact of PUC on LUTS. A total of 539 patients were enrolled in the study. The prostatic urethra was examined by transrectal ultrasonography for PUC, and the location of PUC was divided into 3 areas (proximal, mid, and distal). RESULTS: The characteristics according to the location of PUC were compared using a 1-way analysis of variance test. The Total International Prostate Symptom Score (IPSS), postmicturition symptoms, and overactive bladder symptom score (OABSS) differed significantly among the groups. In the propensity score matching analysis, the proximal- and distal-PUC groups did not have a significantly different urinary flow rate or symptom score when compared to their matched control groups. However, the mid-PUC group had significantly worse urinary symptoms than its matched control group (total IPSS [P=0.001], voiding symptoms [P=0.002], storage symptoms [P=0.041], and OABSS [P=0.015]). The peak urinary flow rate was also lower in the mid-PUC group with borderline significance (P=0.082). On multivariate linear regression analysis, mid-PUC was independently associated with IPSS and OABSS (P=0.035 and P=0.011, respectively). CONCLUSIONS: Only mid-PUC was associated with symptom severity in men with LUTS and a small PV. Our findings suggest that mid-PUC could be a potential causal factor of LUTS, and the midportion of the prostatic urethra might play a pivotal role in the process of micturition.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161136
DOI
10.5213/inj.1732732.366
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실)
Yonsei Authors
이종수(Lee, Jong Soo) ; 이주용(Lee, Joo Yong) ; 조강수(Cho, Kang Su)
사서에게 알리기
  feedback
Files in This Item:
T201704141.pdf Download
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse