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Primary Pulmonary Extranodal Natural Killer/T-cell Lymphoma, Nasal Type Presenting as Diffuse Ground Glass Opacities: a Case Report

Authors
 MyungJin Song  ;  Ji-Ye Kim  ;  Ji Soo Choi  ;  Bora Yoon  ;  MooHyun Kim  ;  Soo-Jeong Kim  ;  Song Yee Kim 
Citation
 Journal of Korean Medical Science, Vol.32(10) : 1727-1730, 2017 
Journal Title
 Journal of Korean Medical Science 
ISSN
 1011-8934 
Issue Date
2017
MeSH
Adrenal Cortex Hormones/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cyclophosphamide/therapeutic use ; Diagnosis, Differential ; Doxorubicin/therapeutic use ; Humans ; Lung Diseases/diagnosis ; Lung Diseases/drug therapy ; Lymphoma, T-Cell/diagnosis* ; Lymphoma, T-Cell/diagnostic imaging ; Lymphoma, T-Cell/drug therapy ; Lymphoma, T-Cell/pathology ; Male ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Prednisone/therapeutic use ; Tomography, X-Ray Computed ; Vincristine/therapeutic use
Keywords
Ground Glass Opacities ; Lung Diseases, Interstitial ; Lung Involvement ; Lymphoma, Extranodal NK-T-Cell
Abstract
Extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTCL) is a rare type of lymphoma that accounts for only 5%-18% of all cases of non-Hodgkin lymphoma (NHL). In published series, 60%-90% of NK/T-cell lymphomas are localized to the nasal and upper airway. We describe a 55-year man who presented with cough, sputum, dyspnea on exertion, and a chest computed tomography scan shows diffuse ground glass opacities (GGOs), suggestive of an interstitial lung disease. He was treated with a corticosteroid and his symptoms improved. However, when the corticosteroid was tapered, his symptoms recurred. The patient underwent a surgical lung biopsy and ENKTCL was diagnosed. We present this case because ENKTCL involving only the lung is very rare but very informative. To our knowledge, our patient is the first case that primary pulmonary ENKTCL is presented with GGOs.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161088
DOI
10.3346/jkms.2017.32.10.1727
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김송이(Kim, Song Yee) ; 김수정(Kim, Soo Jeong) ; 윤보라(Yoon, Bo Ra) ; 최지수(Choi, Ji Soo)
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