Cited 6 times in
Effect of Serial Use of Bone Morphogenetic Protein 2 and Fibroblast Growth Factor 2 on Periodontal Tissue Regeneration
DC Field | Value | Language |
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dc.contributor.author | 김지환 | - |
dc.contributor.author | 박영범 | - |
dc.contributor.author | 조성원 | - |
dc.date.accessioned | 2018-07-20T08:18:17Z | - |
dc.date.available | 2018-07-20T08:18:17Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1056-6163 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161072 | - |
dc.description.abstract | PURPOSE: This study evaluates the synergistic effect of serial application of bone morphogenetic protein 2 (BMP2) and fibroblast growth factor 2 (FGF2) on both new bone formation and periodontal tissue regeneration using 1-wall intrabony defect in mongrel dogs. MATERIALS AND METHODS: One-wall defects were created at the mesial aspect of the mandibular first molars of 6 male mongrel dogs. Each mandibular defect received 1 of the 2 experimental treatments randomly (BMP2 or BMP2 + FGF2), and it was allowed to heal for either 4 or 8 weeks postoperatively. Histologic and histomorphometric analyses were performed for the evaluation of the overall healing patterns of new bone formation and periodontal tissue regeneration. RESULTS: The results showed that after 8 weeks, serial application of BMP2 and FGF2 significantly improved the periodontal tissue regeneration, whereas application of BMP2 only showed greater new bone formation after 4 weeks. CONCLUSIONS: The serial application of BMP2 and FGF2 may have synergistic effects on periodontal tissue regeneration over time. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Williams & Wilkins | - |
dc.relation.isPartOf | IMPLANT DENTISTRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effect of Serial Use of Bone Morphogenetic Protein 2 and Fibroblast Growth Factor 2 on Periodontal Tissue Regeneration | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry | - |
dc.contributor.department | Dept. of Prosthodontics | - |
dc.contributor.googleauthor | Lee, Ah-Reum | - |
dc.contributor.googleauthor | Choi, Hyunmin | - |
dc.contributor.googleauthor | Kim, Jee-Hwan | - |
dc.contributor.googleauthor | Cho, Sung-Won | - |
dc.contributor.googleauthor | Park, Young-Bum | - |
dc.identifier.doi | 10.1097/ID.0000000000000624 | - |
dc.contributor.localId | A01006 | - |
dc.contributor.localId | A01567 | - |
dc.contributor.localId | A03837 | - |
dc.relation.journalcode | J01041 | - |
dc.identifier.eissn | 1538-2982 | - |
dc.identifier.pmid | 28719568 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00008505-201710000-00005&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Kim, Jee Hwan | - |
dc.contributor.alternativeName | Park, Young Bum | - |
dc.contributor.alternativeName | Cho, Sung Won | - |
dc.contributor.affiliatedAuthor | Kim, Jee Hwan | - |
dc.contributor.affiliatedAuthor | Park, Young Bum | - |
dc.contributor.affiliatedAuthor | Cho, Sung Won | - |
dc.citation.volume | 26 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 664 | - |
dc.citation.endPage | 673 | - |
dc.identifier.bibliographicCitation | IMPLANT DENTISTRY, Vol.26(5) : 664-673, 2017 | - |
dc.identifier.rimsid | 60962 | - |
dc.type.rims | ART | - |
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