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Exploring for the optimal structural design for the 3D-printing technology for cranial reconstruction: a biomechanical and histological study comparison of solid vs. porous structure

 Jun Young Lim  ;  Namhyun Kim  ;  Jong-Chul Park  ;  Sun K. Yoo  ;  Dong Ah Shin  ;  Kyu-Won Shim 
 CHILDS NERVOUS SYSTEM, Vol.33(9) : 1553-1562, 2017 
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3D-printing ; Additive manufacturing ; Biomechanical strength ; Bone induction rate ; Bone-implant contact ; Cranioplasty
PURPOSE: Cranioplasty for recovering skull defects carries the risk for a number of complications. Various materials are used, including autologous bone graft, metallic materials, and non-metallic materials, each of which has advantages and disadvantages. If the use of autologous bone is not feasible, those artificial materials also have constraints in the case of complex anatomy and/or irregular defects. MATERIAL AND METHODS: This study used metal 3D-printing technology to overcome these existing drawbacks and analyze the clinical and mechanical performance requirements. To find an optimal structure that satisfied the structural and mechanical stability requirements, we evaluated biomechanical stability using finite element analysis (FEA) and mechanical testing. To ensure clinical applicability, the model was subjected to histological evaluation. Each specimen was implanted in the femur of a rabbit and was evaluated using histological measurements and push-out test. RESULTS AND CONCLUSION: We believe that our data will provide the basis for future applications of a variety of unit structures and further clinical trials and research, as well as the direction for the study of other patient-specific implants.
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1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Hyun(김남현)
Park, Jong Chul(박종철) ORCID logo https://orcid.org/0000-0003-0083-5991
Shin, Dong Ah(신동아) ORCID logo https://orcid.org/0000-0002-5225-4083
Shim, Kyu Won(심규원) ORCID logo https://orcid.org/0000-0002-9441-7354
Yoo, Sun Kook(유선국) ORCID logo https://orcid.org/0000-0002-6032-4686
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