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Associates and Prognosis of Giant Left Atrium; Single Center Experience

DC FieldValueLanguage
dc.contributor.author권혁문-
dc.contributor.author김종윤-
dc.contributor.author김효은-
dc.contributor.author민필기-
dc.contributor.author윤영원-
dc.contributor.author이병권-
dc.contributor.author임세중-
dc.contributor.author최성민-
dc.contributor.author최의영-
dc.contributor.author홍범기-
dc.date.accessioned2018-07-20T08:14:30Z-
dc.date.available2018-07-20T08:14:30Z-
dc.date.issued2017-
dc.identifier.issn1975-4612-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161008-
dc.description.abstractBackground: Left atrial (LA) remodeling develops as a result of longstanding pressure overload. However, determinants and clinical outcome of excessive remodeling, so called giant left atrium (GLA), are not clear. Methods: Clinical characteristics of patients with GLA (antero-posterior diameter higher than 65 mm), including echo-Doppler parameters, and follow-up clinical outcomes from a tertiary referral hospital were investigated. Results: Among 68519 consecutive primary patients who underwent echocardiography over a period of 10 years, data from 163 GLA cases (0.24%) were analyzed. Main causes were significant rheumatic mitral stenosis (n = 58, 36%); other causes comprised significant rheumatic mitral regurgitation (MR; n = 10, 6%), mitral valve (MV) prolapse or congenital mitral valvular disease (MVD) (n = 20, 12%), and functional MR (n = 25, 15%). However, mild rheumatic MV disease (n = 4, 3%) or left ventricular (LV) systolic or diastolic dysfunction without significant MR (n = 46, 28%) were also causes of GLA. During median follow-up of 22 months, 42 cases (26%) underwent composite events. MV surgery was related to lower rate of composite events. In multivariate analysis, MV surgery, elevated pulmonary arterial systolic pressure, and increased LA volume index were independent predictors of future events (p < 0.05) regardless of underlying diseases or history of MV surgery. Conclusion: Although rheumatic MVD with atrial fibrillation is the main contributor to GLA, longstanding atrial fibrillation with LV dysfunction but without MVD also could be related to GLA. Even in GLA state, accurate measurement of LA volume is crucial for risk stratification for future events, regardless of underlying disease.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean, English-
dc.publisherKorean Society of Echocardiography-
dc.relation.isPartOfJournal of Cardiovascular Ultrasound-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAssociates and Prognosis of Giant Left Atrium; Single Center Experience-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorHyoeun Kim-
dc.contributor.googleauthorYoung-Ah Park-
dc.contributor.googleauthorSung Min Choi-
dc.contributor.googleauthorHyemoon Chung-
dc.contributor.googleauthorJong-Youn Kim-
dc.contributor.googleauthorPil-Ki Min-
dc.contributor.googleauthorYoung Won Yoon-
dc.contributor.googleauthorByoung Kwon Lee-
dc.contributor.googleauthorBum-Kee Hong-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorHyuck Moon Kwon-
dc.contributor.googleauthorEui-Young Choi-
dc.identifier.doi10.4250/jcu.2017.25.3.84-
dc.contributor.localIdA00260-
dc.contributor.localIdA00926-
dc.contributor.localIdA01203-
dc.contributor.localIdA01412-
dc.contributor.localIdA02580-
dc.contributor.localIdA02793-
dc.contributor.localIdA03372-
dc.contributor.localIdA04805-
dc.contributor.localIdA04165-
dc.contributor.localIdA04394-
dc.relation.journalcodeJ01298-
dc.identifier.eissn2005-9655-
dc.identifier.pmid29093770-
dc.subject.keywordCardiovascular events-
dc.subject.keywordEchocardiography-
dc.subject.keywordLeft atrium-
dc.subject.keywordRemodeling-
dc.contributor.alternativeNameKwon, Hyuck Moon-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.alternativeNameKim, Hyo Eun-
dc.contributor.alternativeNameMin, Pil Ki-
dc.contributor.alternativeNameYoon, Young Won-
dc.contributor.alternativeNameLee, Byoung Kwon-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.alternativeNameChoi, Sung Min-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameHong, Bum Kee-
dc.contributor.affiliatedAuthorKwon, Hyuck Moon-
dc.contributor.affiliatedAuthorKim, Jong Youn-
dc.contributor.affiliatedAuthorKim, Hyo Eun-
dc.contributor.affiliatedAuthorMin, Pil Ki-
dc.contributor.affiliatedAuthorYoon, Young Won-
dc.contributor.affiliatedAuthorLee, Byoung Kwon-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorChoi, Sung Min-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorHong, Bum Kee-
dc.citation.volume25-
dc.citation.number3-
dc.citation.startPage84-
dc.citation.endPage90-
dc.identifier.bibliographicCitationJournal of Cardiovascular Ultrasound, Vol.25(3) : 84-90, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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