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Peripapillary Choroidal Thickness Change of Polypoidal Choroidal Vasculopathy after Anti-vascular Endothelial Growth Factor

DC Field Value Language
dc.contributor.author강의천-
dc.contributor.author고형준-
dc.contributor.author김서희-
dc.contributor.author이규호-
dc.date.accessioned2018-07-20T08:11:21Z-
dc.date.available2018-07-20T08:11:21Z-
dc.date.issued2017-
dc.identifier.issn1011-8942-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160940-
dc.description.abstractPURPOSE: To investigate the peripapillary choroidal thickness (PCT) of polypoidal choroidal vasculopathy (PCV) and exudative age-related macular degeneration (AMD) and to evaluate their responses to anti-vascular endothelial growth factor (VEGF). METHODS: Thirty eyes with PCV and 25 eyes with exudative AMD who were treatment naïve were included in this study. PCT and subfoveal choroidal thickness were evaluated both before and after intravitreal anti-VEGF. RESULTS: The initial mean PCT of PCV (153.78 ± 56.23 μm) was thicker than that of exudative AMD (88.77 ± 23.11 μm, p < 0.001). Temporal, superior, nasal, and inferior PCTs of PCV were all thicker than those observedin exudative AMD (all p < 0.05). After anti-VEGF, the mean PCT of PCV was significantly reduced (134.17 ± 41.66 μm, p < 0.001), but the same was not true not in exudative AMD (86.87 ± 22.54 μm, p = 0.392). PCTshowed a similar tendency in all quadrants. CONCLUSIONS: PCV exhibits a thick choroid in the peripapillary region. PCT decreases after anti-VEGF in PCV but not in exudative AMD. In exudative AMD, subfoveal choroidal thickness decreased, but that in the peripapillary region did not.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKJO-
dc.relation.isPartOfKorean Journal of Ophthalmology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAngiogenesis Inducing Agents/administration & dosage*-
dc.subject.MESHBevacizumab/administration & dosage-
dc.subject.MESHChoroid/blood supply*-
dc.subject.MESHChoroid/pathology-
dc.subject.MESHChoroid Diseases/diagnosis*-
dc.subject.MESHChoroid Diseases/drug therapy-
dc.subject.MESHFemale-
dc.subject.MESHFluorescein Angiography-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHFundus Oculi-
dc.subject.MESHHumans-
dc.subject.MESHIntravitreal Injections-
dc.subject.MESHMacula Lutea/pathology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOptic Disk/pathology*-
dc.subject.MESHRanibizumab/administration & dosage-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, Optical Coherence-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHVascular Endothelial Growth Factor A/antagonists & inhibitors*-
dc.subject.MESHVisual Acuity-
dc.titlePeripapillary Choroidal Thickness Change of Polypoidal Choroidal Vasculopathy after Anti-vascular Endothelial Growth Factor-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorKyou Ho Lee-
dc.contributor.googleauthorSeo Hee Kim-
dc.contributor.googleauthorJi Min Lee-
dc.contributor.googleauthorEui Chun Kang-
dc.contributor.googleauthorHyoung Jun Koh-
dc.identifier.doi10.3341/kjo.2016.0101-
dc.contributor.localIdA00073-
dc.contributor.localIdA00152-
dc.contributor.localIdA05307-
dc.contributor.localIdA04995-
dc.relation.journalcodeJ02931-
dc.identifier.eissn2092-9382-
dc.identifier.pmid28994269-
dc.subject.keywordAnti-vascular endothelial growth factor-
dc.subject.keywordChoroid-
dc.subject.keywordMacular degeneration-
dc.subject.keywordPolypoidal choroidal vasculopathy-
dc.contributor.alternativeNameKang, Eui Chun-
dc.contributor.alternativeNameKoh, Hyoung Jun-
dc.contributor.alternativeNameKim, Seo Hee-
dc.contributor.alternativeNameLee, Kyou Ho-
dc.contributor.affiliatedAuthorKang, Eui Chun-
dc.contributor.affiliatedAuthorKoh, Hyoung Jun-
dc.contributor.affiliatedAuthorKim, Seo Hee-
dc.contributor.affiliatedAuthorLee, Kyou Ho-
dc.citation.volume31-
dc.citation.number5-
dc.citation.startPage431-
dc.citation.endPage438-
dc.identifier.bibliographicCitationKorean Journal of Ophthalmology, Vol.31(5) : 431-438, 2017-
dc.identifier.rimsid60834-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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