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The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

Authors
 Hae Jun Song  ;  Chul Jong Park  ;  Tae Yoon Kim  ;  Yong Beom Choe  ;  Seok-Jong Lee  ;  Nack In Kim  ;  Jae We Cho  ;  Jie Hyun Jeon  ;  Min Soo Jang  ;  Jai Il Youn  ;  Myung Hwa Kim  ;  Joonsoo Park  ;  Ki Ho Kim  ;  Byung Soo Kim  ;  Sang Woong Youn  ;  Joo-Heung Lee  ;  Min-Geol Lee  ;  Sung Ku Ahn  ;  Young Ho Won  ;  Seok Kweon Yun  ;  Bong Seok Shin  ;  Seong Jun Seo  ;  Ji Yeoun Lee  ;  Kwang Joong Kim  ;  Young Suck Ro  ;  Youngdoe Kim  ;  Dae Young Yu  ;  Jee-Ho Choi 
Citation
 Annals of Dermatology, Vol.29(4) : 462-470, 2017 
Journal Title
 Annals of Dermatology 
ISSN
 1013-9087 
Issue Date
2017
Keywords
Epidemiologic studies ; Korea ; Psoriasis
Abstract
BACKGROUND: Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. OBJECTIVE: To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea. METHODS: This multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected. RESULTS: A total of 1,260 patients completed the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (<40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m2; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI <10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist circumference of female, and treatment experiences with phototherapy, systemic agents, and biologics. CONCLUSION: This was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemiologic characteristics and clinical profiles of this patient population.
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DOI
10.5021/ad.2017.29.4.462
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
이민걸(Lee, Min Geol) ORCID logo https://orcid.org/0000-0001-7040-5335
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160931
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