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Detection of mechanical complications related to the potential risk of sudden cardiac death in patients with pulmonary arterial hypertension by computed tomography

DC Field Value Language
dc.contributor.author성지민-
dc.contributor.author심지영-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.contributor.author정조원-
dc.contributor.author조인정-
dc.contributor.author홍그루-
dc.contributor.author이상은-
dc.date.accessioned2018-07-20T08:08:28Z-
dc.date.available2018-07-20T08:08:28Z-
dc.date.issued2017-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160873-
dc.description.abstractBACKGROUND: We explored the value of cardiac computed tomography (CT) for the detection and prediction of mechanical complications related to the risk of sudden cardiac death (SCD) in pulmonary arterial hypertension (PAH) patients. METHODS: PAH patients (n=60, mean age 47±15, 31.7% male) with pulmonary artery (PA) enlargement (≥40mm) by echocardiography were studied with cardiac CT. Complications explored were the presence of left main coronary artery (LM) compression, airway compression, PA dissection and PA thrombosis in relation to diameters of main PA (MPA) which were measured in (1) axial plane (MPAAx) and (2) LM oblique view (MPALMobq). RESULTS: Mechanical complications were found in 21 patients (35.0%): LM compression in 20 patients; airway compression in 3 patients; and PA thrombosis in 4 patients. Patients with complications had more dilated MPALMobq than patients without complication (59.4±13.0mm vs. 42.4±7.0mm, p<0.001). The area under the receiver operating characteristic curve for MPALMobq was 0.889 (95% confidence interval: 0.795 to 0.983, p<0.001) with the highest discriminating sensitivity and specificity being 90.5% and 69.2%, respectively at MPALMobq of 45mm. MPAAx failed to predict the presence of mechanical complications (p>0.05). CONCLUSION: MPALMobq≥45mm was significantly associated with the presence of mechanical complications of PAH. Evaluation with CT should be considered in PAH patients with dilated MPA.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAneurysm, Dissecting/diagnostic imaging-
dc.subject.MESHAneurysm, Dissecting/etiology-
dc.subject.MESHAneurysm, Dissecting/mortality-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHDeath, Sudden, Cardiac/epidemiology*-
dc.subject.MESHDilatation, Pathologic/diagnostic imaging-
dc.subject.MESHDilatation, Pathologic/etiology-
dc.subject.MESHDilatation, Pathologic/mortality-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHypertension, Pulmonary/complications-
dc.subject.MESHHypertension, Pulmonary/diagnostic imaging*-
dc.subject.MESHHypertension, Pulmonary/mortality*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPulmonary Artery/diagnostic imaging-
dc.subject.MESHRisk Factors-
dc.subject.MESHTomography, X-Ray Computed*/methods-
dc.titleDetection of mechanical complications related to the potential risk of sudden cardiac death in patients with pulmonary arterial hypertension by computed tomography-
dc.typeArticle-
dc.contributor.collegeResearch Institutes-
dc.contributor.departmentYonsei Cardiovascular Research Institute-
dc.contributor.googleauthorSang-Eun Lee-
dc.contributor.googleauthorJi Hyun Im-
dc.contributor.googleauthorJi Min Sung-
dc.contributor.googleauthorIn-Jeong Cho-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorNamsik Chung-
dc.contributor.googleauthorJo Won Jung-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.identifier.doi10.1016/j.ijcard.2017.05.090-
dc.contributor.localIdA01955-
dc.contributor.localIdA02213-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA03720-
dc.contributor.localIdA03892-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ01093-
dc.identifier.eissn1874-1754-
dc.identifier.pmid28576625-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0167527317319125-
dc.subject.keywordCardiac computed tomography-
dc.subject.keywordPulmonary artery-
dc.subject.keywordPulmonary hypertension-
dc.subject.keywordSudden cardiac death-
dc.contributor.alternativeNameSung, Ji Min-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameJung, Jo Won-
dc.contributor.alternativeNameCho, In Jeong-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorSung, Ji Min-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorJung, Jo Won-
dc.contributor.affiliatedAuthorCho, In Jeong-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.citation.volume243-
dc.citation.startPage460-
dc.citation.endPage465-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.243 : 460-465, 2017-
dc.identifier.rimsid60756-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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