Cited 8 times in
CLINICAL OUTCOMES OF INTRAVITREAL BEVACIZUMAB VERSUS PHOTODYNAMIC THERAPY WITH OR WITHOUT BEVACIZUMAB FOR MYOPIC CHOROIDAL NEOVASCULARIZATION: A 7-Year Follow-up Study
DC Field | Value | Language |
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dc.contributor.author | 강의천 | - |
dc.contributor.author | 고형준 | - |
dc.contributor.author | 성공제 | - |
dc.date.accessioned | 2018-07-20T08:04:28Z | - |
dc.date.available | 2018-07-20T08:04:28Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0275-004X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160814 | - |
dc.description.abstract | PURPOSE: To compare the long-term visual outcomes of intravitreal bevacizumab (IVB) with those of photodynamic therapy (PDT) for myopic choroidal neovascularization over a 7-year period. METHODS: Eyes treated with IVB (17 eyes) or PDT (20 eyes) that were followed up for at least 7 years were included in this retrospective study. Myopic maculopathy was classified according to the international photographic classification before treatment. The best-corrected visual acuity (BCVA) and the chorioretinal atrophy (CRA) size were measured before and after treatment over a 7-year period. RESULTS: The mean change in BCVA at 7 years was greater in the IVB group than in the PDT group (P = 0.044). While BCVA improved from baseline throughout the 7-year period in the IVB group (P = 0.029), there was no improvement in the PDT group (P = 0.266). In subgroup analysis for 18 eyes with preoperative tessellated fundi (Category 1), there was no difference in BCVA improvement (P = 0.166) and CRA size between the 2 groups at 7 years. However, for 17 eyes with preoperative diffuse CRA (Category 2), BCVA remained unchanged in the IVB group and decreased in the PDT group (P = 0.030) at 7 years. CONCLUSION: IVB resulted in superior long-term functional and anatomical outcomes compared with PDT. In particular, PDT resulted in a greater BCVA decrease and CRA increase compared with IVB in eyes with preoperative diffuse CRA. However, the clinical outcomes were not different in eyes with preoperative tessellated fundi. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angiogenesis Inhibitors/therapeutic use* | - |
dc.subject.MESH | Bevacizumab/therapeutic use* | - |
dc.subject.MESH | Choroidal Neovascularization/drug therapy* | - |
dc.subject.MESH | Choroidal Neovascularization/physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intravitreal Injections | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myopia | - |
dc.subject.MESH | Myopia, Degenerative/drug therapy* | - |
dc.subject.MESH | Myopia, Degenerative/physiopathology | - |
dc.subject.MESH | Photochemotherapy/methods* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Visual Acuity | - |
dc.title | CLINICAL OUTCOMES OF INTRAVITREAL BEVACIZUMAB VERSUS PHOTODYNAMIC THERAPY WITH OR WITHOUT BEVACIZUMAB FOR MYOPIC CHOROIDAL NEOVASCULARIZATION: A 7-Year Follow-up Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Ophthalmology | - |
dc.contributor.googleauthor | Kang, Eui Chun | - |
dc.contributor.googleauthor | Seo, Jeong Gi | - |
dc.contributor.googleauthor | Kim, Bo Ram | - |
dc.contributor.googleauthor | Koh, Hyoung Jun | - |
dc.identifier.doi | 10.1097/IAE.0000000000001421 | - |
dc.contributor.localId | A00073 | - |
dc.contributor.localId | A00152 | - |
dc.contributor.localId | A01946 | - |
dc.relation.journalcode | J02621 | - |
dc.identifier.eissn | 1539-2864 | - |
dc.identifier.pmid | 27997511 | - |
dc.identifier.url | https://oce.ovid.com/article/00006982-201709000-00019/HTML | - |
dc.contributor.alternativeName | Kang, Eui Chun | - |
dc.contributor.alternativeName | Koh, Hyoung Jun | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Kang, Eui Chun | - |
dc.contributor.affiliatedAuthor | Koh, Hyoung Jun | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.citation.volume | 37 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1775 | - |
dc.citation.endPage | 1783 | - |
dc.identifier.bibliographicCitation | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Vol.37(9) : 1775-1783, 2017 | - |
dc.identifier.rimsid | 60698 | - |
dc.type.rims | ART | - |
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