Cited 0 times in

Protein C 결핍에서 발생한 소모성 응고질환으로 인한 뇌내출혈로 야기된 뇌성마비 환자에 대한 증례기록

DC Field Value Language
dc.contributor.author나동욱-
dc.contributor.author박은숙-
dc.contributor.author박천웅-
dc.contributor.author이영목-
dc.contributor.author최자영-
dc.date.accessioned2018-07-20T08:03:23Z-
dc.date.available2018-07-20T08:03:23Z-
dc.date.issued2017-
dc.identifier.issn1226-6884-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160792-
dc.description.abstractProtein C (PROC) is a potent anticoagulant inactivating coagulation factors Va and VIIIa. PROC deficiency is very rare condition inherited as an autosomal dominant or recessive trait, and associated with various thromboembolic and ischemic conditions. Moreover, severe form of PROC deficiency can cause fatal hemorrhagic complications due to consumptive coagulopathy. We reported two children with hemorrhagic stroke who were diagnosed as severe PROC deficiency caused by two different types of compound heterozygous PROC gene mutations. We described results of laboratory tests, genetic analysis, brain magnetic resonance images, and functional outcomes. Both children received prophylactic anticoagulation therapy and presented with purple-colored skin lesions during rehabilitation. Purpura fulminans caused by insufficient anticoagulation should be differentiated from hematoma caused by excessive anticoagulation therapy in these children.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean-
dc.publisher대한소아신경학회-
dc.relation.isPartOfJournal of the Korean Child Neurology Society-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleProtein C 결핍에서 발생한 소모성 응고질환으로 인한 뇌내출혈로 야기된 뇌성마비 환자에 대한 증례기록-
dc.title.alternativeCerebral Palsy due to Intracranial Hemorrhage Caused by Consumptive Coagulopathy in Protein C Deficiency: A Case Report-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Rehabilitation Medicine-
dc.contributor.googleauthor조유나-
dc.contributor.googleauthor이영목-
dc.contributor.googleauthor박은숙-
dc.contributor.googleauthor최자영-
dc.contributor.googleauthor박천웅-
dc.contributor.googleauthor나동욱-
dc.contributor.localIdA01230-
dc.contributor.localIdA01611-
dc.contributor.localIdA05341-
dc.contributor.localIdA02955-
dc.contributor.localIdA04170-
dc.relation.journalcodeJ01815-
dc.subject.keywordPurpura fulminans-
dc.subject.keywordCerebral palsy-
dc.subject.keywordProtein C deficiency-
dc.contributor.alternativeNameRha, Dong Wook-
dc.contributor.alternativeNamePark, Eun Sook-
dc.contributor.alternativeNamePark, Chunung-
dc.contributor.alternativeNameLee, Young Mock-
dc.contributor.alternativeNameChoi, Ja Young-
dc.contributor.affiliatedAuthorRha, Dong Wook-
dc.contributor.affiliatedAuthorPark, Eun Sook-
dc.contributor.affiliatedAuthorPark, Chunung-
dc.contributor.affiliatedAuthorLee, Young Mock-
dc.contributor.affiliatedAuthorChoi, Ja Young-
dc.citation.volume25-
dc.citation.number1-
dc.citation.startPage44-
dc.citation.endPage47-
dc.identifier.bibliographicCitationJournal of the Korean Child Neurology Society, Vol.25(1) : 44-47, 2017-
dc.identifier.rimsid61733-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.