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Semliki Forest Virus 감염은 뉴우런의 탈수초를 유발한다
DC Field | Value | Language |
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dc.contributor.author | 김현주 | - |
dc.contributor.author | 홍성갑 | - |
dc.date.accessioned | 2018-07-20T08:00:15Z | - |
dc.date.available | 2018-07-20T08:00:15Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2234-4772 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160747 | - |
dc.description.abstract | We constructed a population of myelinated cells with co-culture of neuronal cells and Schwann cells from DRG. Schwann cells and neuronal cells were isolated from dorsal root ganglion (DRG) in embryos of rat in vitro respectively. The cultured Schwann cells and cultured neuronal cells, respectively were co-cultured in a same plate. This procedure contains following four steps: first step of suspension of the embryonic dorsal root ganglion cells, second step of addition of anti-mitoticcocktail, third step of purification of dorsal root cells, and fourth step of addition of Schwann cells to dorsal root ganglion cells. These cells were performed accomplishment of myelination. This myelinated co-culture system was infected by Semliki forest virus and then induced demyelination processing in this myelinated co-culture. We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 한국해양정보통신학회 | - |
dc.relation.isPartOf | Journal of the Korean Institute of Maritime Information & Communication Sciences (한국정보통신학회논문지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Semliki Forest Virus 감염은 뉴우런의 탈수초를 유발한다 | - |
dc.title.alternative | Infection of Semliki Forest Virus Induces Demyelination of Neuron | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine | - |
dc.contributor.googleauthor | 김현주 | - |
dc.contributor.googleauthor | 사영희 | - |
dc.contributor.googleauthor | 홍성갑 | - |
dc.identifier.doi | 10.6109/jkiice.2017.21.6.1212 | - |
dc.contributor.localId | A01135 | - |
dc.contributor.localId | A04827 | - |
dc.relation.journalcode | J01830 | - |
dc.identifier.eissn | 2288-4165 | - |
dc.subject.keyword | demyelination | - |
dc.subject.keyword | myelination | - |
dc.subject.keyword | peripheral myelin protein 22 | - |
dc.subject.keyword | Semliki forest virus | - |
dc.contributor.alternativeName | Kim, Hyun Zu | - |
dc.contributor.alternativeName | Hong, Seong Karp | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Joo | - |
dc.contributor.affiliatedAuthor | Hong, Seong Karp | - |
dc.citation.volume | 21 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1212 | - |
dc.citation.endPage | 1217 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Institute of Maritime Information & Communication Sciences (한국정보통신학회논문지), Vol.21(6) : 1212-1217, 2017 | - |
dc.identifier.rimsid | 60633 | - |
dc.type.rims | ART | - |
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