YUHSpace

BROWSE

Export
282 547

Cited 0 times in

Dexamethasone Intravitreal Implant Rescue Treatment for Bevacizumab Refractory Macular Edema Secondary to Branch Retinal Vein Occlusion

DC Field Value Language
dc.contributor.author강의천-
dc.contributor.author고형준-
dc.contributor.author이규호-
dc.date.accessioned2018-07-20T07:55:16Z-
dc.date.available2018-07-20T07:55:16Z-
dc.date.issued2017-
dc.identifier.issn1011-8942-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160667-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKJO-
dc.relation.isPartOfKorean Journal of Ophthalmology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAngiogenesis Inhibitors/administration & dosage-
dc.subject.MESHBevacizumab/administration & dosage*-
dc.subject.MESHDexamethasone/administration & dosage*-
dc.subject.MESHDrug Implants-
dc.subject.MESHDrug Resistance*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGlucocorticoids/administration & dosage-
dc.subject.MESHHumans-
dc.subject.MESHIntravitreal Injections-
dc.subject.MESHMacular Edema/diagnosis-
dc.subject.MESHMacular Edema/drug therapy*-
dc.subject.MESHMacular Edema/etiology-
dc.subject.MESHMale-
dc.subject.MESHRetinal Vein Occlusion/complications*-
dc.subject.MESHRetinal Vein Occlusion/diagnosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, Optical Coherence-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHVisual Acuity*-
dc.titleDexamethasone Intravitreal Implant Rescue Treatment for Bevacizumab Refractory Macular Edema Secondary to Branch Retinal Vein Occlusion-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorKyou Ho Lee-
dc.contributor.googleauthorEui Chun Kang-
dc.contributor.googleauthorHyoung Jun Koh-
dc.identifier.doi10.3341/kjo.2017.31.2.108-
dc.contributor.localIdA00073-
dc.contributor.localIdA00152-
dc.contributor.localIdA04995-
dc.relation.journalcodeJ02931-
dc.identifier.eissn2092-9382-
dc.identifier.pmid28367038-
dc.subject.keywordPURPOSE: To evaluate the prognostic factors and outcomes of dexamethasone intravitreal implant (DEX implant) for intravitreal bevacizumab refractory macular edema secondary to branch retinal vein occlusion (BRVO). METHODS: This was a retrospective, interventional case series. Medical records were reviewed, and a total of 38 eyes that were treated with DEX implant for macular edema secondary to BRVO that did not respond to at least two consecutive intravitreal bevacizumab injections (IBIs) were included. Best-corrected visual acuity (BCVA), central subfield macular thickness, and central subfoveal choroidal thickness were evaluated at baseline, 2 months, and 6 months after DEX implantation. RESULTS: Patients had undergone an average of 6.32 ± 4.66 prior IBI treatments. The average BCVA improved from 0.53 ± 0.26 to 0.41 ± 0.25 and 0.44 ± 0.23 logarithm of the minimal angle of resolution (logMAR) at 2 and 6 months, respectively (p < 0.001). The average central subfield macular thickness was 504.00 ± 121.54 µm at baseline and changed to 293.21 ± 74.17 µm and 427.28 ± 119.57 µm at 2 and 6 months, respectively (p < 0.001 and p = 0.002). Average central subfoveal choroidal thickness was 237.46 ± 92.21 µm at baseline and changed to 204.75 ± 74.74 µm and 226.86 ± 90.77 µm at 2 and 6 months, respectively (p < 0.001 and p = 0.455). Twenty-two eyes (58%) gained ≥0.1 logMAR at 2 months, while 16 eyes showed no improvement. Low BCVA at symptom presentation, low baseline BCVA, and shorter duration of macular edema were correlated with increased BCVA after treatment. CONCLUSIONS: The DEX implant improves functional and anatomical outcomes for up to 6 months in about half of the patients treated with IBI refractory macular edema secondary to BRVO, particularly in patients with low initial and baseline BCVA.-
dc.contributor.alternativeNameKang, Eui Chun-
dc.contributor.alternativeNameKoh, Hyoung Jun-
dc.contributor.alternativeNameLee, Kyou Ho-
dc.contributor.affiliatedAuthorKang, Eui Chun-
dc.contributor.affiliatedAuthorKoh, Hyoung Jun-
dc.contributor.affiliatedAuthorLee, Kyou Ho-
dc.citation.volume31-
dc.citation.number2-
dc.citation.startPage108-
dc.citation.endPage114-
dc.identifier.bibliographicCitationKorean Journal of Ophthalmology, Vol.31(2) : 108-114, 2017-
dc.identifier.rimsid41839-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Show simple item record Find it @ YMLIB

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

  • License
    sherpa_romeo
    sherpa_juliet

OAK

DSpace Software Copyright © 2002-2017 Duraspace Yonsei University Medical Library All right Reserves. / TEL:02-2228-2915 /
YUHSpace는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.

Browse

Links