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Cell Microarray Technologies for High-Throughput Cell-Based Biosensors

Authors
 Hye Jin Hong  ;  Woong Sub Koom  ;  Won-Gun Koh 
Citation
 SENSORS, Vol.17(6) : E1293, 2017 
Journal Title
 SENSORS 
Issue Date
2017
MeSH
Biosensing Techniques* ; Drug Discovery ; Humans ; Microtechnology ; Miniaturization ; Tissue Array Analysis
Keywords
biosensing ; cell microarray ; cell-based biosensor ; drug discovery ; microfabrication ; positional array ; suspension array ; toxicology
Abstract
Due to the recent demand for high-throughput cellular assays, a lot of efforts have been made on miniaturization of cell-based biosensors by preparing cell microarrays. Various microfabrication technologies have been used to generate cell microarrays, where cells of different phenotypes are immobilized either on a flat substrate (positional array) or on particles (solution or suspension array) to achieve multiplexed and high-throughput cell-based biosensing. After introducing the fabrication methods for preparation of the positional and suspension cell microarrays, this review discusses the applications of the cell microarray including toxicology, drug discovery and detection of toxic agents.
Files in This Item:
T201702787.pdf Download
DOI
10.3390/s17061293
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Koom, Woong Sub(금웅섭) ORCID logo https://orcid.org/0000-0002-9435-7750
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160626
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