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Metabolic risk score and vascular mortality among Korean adults: The Korean metabolic syndrome mortality study

Authors
 Keum Ji Jung  ;  Yon Ho Jee  ;  Sun Ha Jee 
Citation
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH, Vol.29(2) : 122-131, 2017 
Journal Title
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH 
ISSN
 1010-5395 
Issue Date
2017
MeSH
Adult ; Atherosclerosis/mortality ; Coronary Artery Disease/mortality ; Female ; Humans ; Male ; Metabolic Syndrome/epidemiology* ; Middle Aged ; Proportional Hazards Models ; Republic of Korea/epidemiology ; Retrospective Studies Risk Assessment Stroke/mortality Vascular Diseases/mortality*
Keywords
coronary heart disease ; metabolic syndrome ; risk score ; stroke ; vascular mortality
Abstract
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors. However, rather than using a dichotomous scale, a continuous metabolic syndrome (cMetS) score has been proposed to evaluate MetS because current MetS criteria do not function well in identifying those at high risk of cardiovascular mortality. The objective of this study was to examine the association between cMetS score and vascular mortality among Korean population. We included 441 411 individuals who visited health promotion centers and were given a medical examination from 1994 to 2004. MetS status, sum of MetS components, and cMetS score were calculated. The individuals with MetS had a higher hazard ratio (HR) for mortality from atherosclerotic vascular disease (HR = 1.54, 95% CI = 1.42-1.67), ischemic heart disease (HR = 1.74, 95% CI = 1.51-2.01), and total stroke (HR = 1.44, 95% CI = 1.28-1.62) when compared with those without MetS. Graded, strong associations between cMetS score and vascular mortality, particularly from ischemic heart disease and ischemic stroke, were observed. Subjects with a cMetS score ≥30 were at about 64 times greater risk for vascular mortality than those with a cMetS score below 0. cMetS score can be used to predict the risk of vascular death and provides a useful guideline to identify individuals at high risk for metabolic syndrome among Koreans.
Full Text
http://journals.sagepub.com/doi/abs/10.1177/1010539516688082
DOI
10.1177/1010539516688082
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Jung, Keum Ji(정금지) ORCID logo https://orcid.org/0000-0003-4993-0666
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160585
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