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Transient neonatal myasthenia gravis due to a mother with ocular onset of anti-muscle specific kinase myasthenia gravis

DC FieldValueLanguage
dc.contributor.author한승한-
dc.contributor.author한진우-
dc.date.accessioned2018-07-20T07:50:44Z-
dc.date.available2018-07-20T07:50:44Z-
dc.date.issued2017-
dc.identifier.issn0960-8966-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160577-
dc.description.abstractWe describe a 27-year-old pregnant female with new onset of conjugate gaze deficit during the third trimester of pregnancy. Repetitive nerve stimulation tests, neostigmine tests, and acetylcholine receptor antibody assays were all negative. The patient delivered a normal healthy baby at a local clinic via cesarean section. The baby became hypotonic and had respiratory failure several minutes after birth. The result of acetylcholine receptor antibody was negative in the neonate. The neonate became healthy spontaneously and was extubated after 21 days of ventilation care. Two months after delivery, the mother developed ptosis and generalized symptoms and subsequent workup revealed she was muscle specific kinase (MuSK) antibody positive. The neonate was presumed to have an anti-MuSK-mediated transient neonatal myasthenia gravis. Although MuSK antibody testing is rarely indicated in ocular myasthenia gravis, MuSK antibody testing is necessary in pregnant women who are presumed ocular myasthenia gravis to warn occurrence of transient neonatal myasthenia gravis.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherPergamon Press-
dc.relation.isPartOfNEUROMUSCULAR DISORDERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAutoantibodies/blood-
dc.subject.MESHAutoantibodies/immunology-
dc.subject.MESHBlepharoptosis/etiology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMyasthenia Gravis/complications-
dc.subject.MESHMyasthenia Gravis/immunology-
dc.subject.MESHMyasthenia Gravis, Neonatal-
dc.subject.MESHPregnancy-
dc.subject.MESHPregnancy Complications/immunology-
dc.subject.MESHReceptor Protein-Tyrosine Kinases/immunology-
dc.subject.MESHReceptors, Cholinergic/immunology-
dc.titleTransient neonatal myasthenia gravis due to a mother with ocular onset of anti-muscle specific kinase myasthenia gravis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorJu-Yeun Lee-
dc.contributor.googleauthorJu-Hong Min-
dc.contributor.googleauthorSueng-Han Han-
dc.contributor.googleauthorJinu Han-
dc.identifier.doi10.1016/j.nmd.2017.03.012-
dc.contributor.localIdA04303-
dc.contributor.localIdA04329-
dc.relation.journalcodeJ02344-
dc.identifier.eissn1873-2364-
dc.identifier.pmid28495046-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0960896617300639-
dc.subject.keywordAnti-muscle-specific kinase-
dc.subject.keywordOcular myasthenia gravis-
dc.subject.keywordPregnancy-
dc.subject.keywordTransient neonatal myasthenia gravis-
dc.contributor.alternativeNameHan, Seung Han-
dc.contributor.alternativeNameHan, Jin U-
dc.contributor.affiliatedAuthorHan, Seung Han-
dc.contributor.affiliatedAuthorHan, Jin U-
dc.citation.volume27-
dc.citation.number7-
dc.citation.startPage655-
dc.citation.endPage657-
dc.identifier.bibliographicCitationNEUROMUSCULAR DISORDERS, Vol.27(7) : 655-657, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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