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A Prospective, Comparative Study of the Pain of Local Anesthesia Using 2% Lidocaine, 2% Lidocaine With Epinephrine, and 2% Lidocaine With Epinephrine-Bupivicaine Mixture for Eyelid Surgery.

DC FieldValueLanguage
dc.contributor.author김창염-
dc.contributor.author윤진숙-
dc.date.accessioned2018-07-20T07:43:43Z-
dc.date.available2018-07-20T07:43:43Z-
dc.date.issued2017-
dc.identifier.issn1078-1439-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160467-
dc.description.abstractPURPOSE: A mixture of 2% lidocaine with epinephrine and bupivacaine was developed to achieve the fast-onset anesthetic effect of lidocaine and the long-lasting effect of bupivacaine. The authors compared pain scores between 2% lidocaine, 2% lidocaine with epinephrine, and 2% lidocaine with epinephrine-bupivicaine mixture during local anesthesia for eyelid surgeries. METHODS: This was a double-blind, randomized, prospective, comparative study. In total, 120 consecutive patients (43 males, 77 females, mean age = 47.2 ± 21.2) who underwent bilateral eyelid surgery under subcutaneous anesthesia were asked to report pain scores for each eye during the first injection of anesthesia. Each patient was randomly assigned to receive 1 of the 3 anesthetic agents in 1 eyelid, and 1 of the remaining 2 agents in the other. RESULTS: The pH values of the 2% lidocaine, 2% lidocaine with epinephrine, and 2% lidocaine with epinephrine-bupivicaine mixture were 6.23 ± 0.21, 4.21 ± 0.37, and 3.87 ± 0.19, respectively. The pain scores of each were 4.3 ± 1.8, 5.1 ± 1.8, and 5.7 ± 1.9, respectively. The 2% lidocaine with epinephrine produced a statistically significantly higher pain score than 2% lidocaine (p = 0.044, generalized estimating equation method). The mixture also showed a significantly higher pain score than 2% lidocaine (p = 0.003, generalized estimating equation method). CONCLUSIONS: Epinephrine seemed to increase subjective pain scores. Compared with 2% lidocaine with epinephrine, 2% lidocaine with epinephrine-bupivicaine mixture was not significantly different in terms of subjective symptoms or pH.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfUrologic Oncology - Seminars and Original Investigations-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAnesthesia, Local/methods*-
dc.subject.MESHAnesthetics, Local/therapeutic use*-
dc.subject.MESHBupivacaine/therapeutic use*-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHEpinephrine/therapeutic use*-
dc.subject.MESHEyelids/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLidocaine/therapeutic use*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOphthalmologic Surgical Procedures*-
dc.subject.MESHPain Measurement-
dc.subject.MESHYoung Adult-
dc.titleA Prospective, Comparative Study of the Pain of Local Anesthesia Using 2% Lidocaine, 2% Lidocaine With Epinephrine, and 2% Lidocaine With Epinephrine-Bupivicaine Mixture for Eyelid Surgery.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Ophthalmology-
dc.contributor.googleauthorJung-woo Han-
dc.contributor.googleauthorSeung Kwan Nah-
dc.contributor.googleauthorSang Yeul Lee-
dc.contributor.googleauthorChang Yeom Kim-
dc.contributor.googleauthorJin Sook Yoon-
dc.contributor.googleauthorSun Young Jang-
dc.identifier.doi10.1097/IOP.0000000000000675-
dc.contributor.localIdA01043-
dc.contributor.localIdA02611-
dc.relation.journalcodeJ02774-
dc.identifier.eissn1873-2496-
dc.identifier.pmid26974418-
dc.identifier.urlhttps://oce.ovid.com/article/00002341-201703000-00011/HTML-
dc.contributor.alternativeNameKim, Chang Yeom-
dc.contributor.alternativeNameYoon, Jin Sook-
dc.contributor.affiliatedAuthorKim, Chang Yeom-
dc.contributor.affiliatedAuthorYoon, Jin Sook-
dc.citation.volume33-
dc.citation.number2-
dc.citation.startPage132-
dc.citation.endPage135-
dc.identifier.bibliographicCitationUrologic Oncology - Seminars and Original Investigations, Vol.33(2) : 132-135, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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