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법랑모세포섬유-치아종으로부터 발생한 법랑모세포섬유육종 -증례보고-

Other Titles
 A case of Ameloblastic Fibrosarcoma Transformed from Ameloblastic Fibro-odontoma 
Authors
 Bazarsad Shadavlonjid  ;  조은애  ;  남웅  ;  김현실  ;  육종인  ;  김진 
Citation
 Korean Journal of Oral and Maxillofacial Pathology (대한구강악안면병리학회지), Vol.41(1) : 45-50, 2017 
Journal Title
 Korean Journal of Oral and Maxillofacial Pathology (대한구강악안면병리학회지) 
ISSN
 1225-1577 
Issue Date
2017
Keywords
Ameloblastic fibro-odontoma ; Ameloblastic fibrosarcoma ; Malignant transformation
Abstract
Ameloblastic fibrosarcoma (AFS) is an extremely rare malignant odontogenic tumor characterized with benign ameloblastic cells islands and malignant mesenchymal component. While two-thirds of AFS seem to arise de novo, but one-third develops from recurrent ameloblastic fibroma (AF) or ameloblastic fibro-odontomas (AFO). Pathological distinction of malignant transformation is essential for appropriate treatment. The patient was a 28 years old man. Since the primary tumor was excised, the mass recurred 2 years later. The recurrent tumor was diagnosed as AFS. Chief complaint was pain in the right mandible. Computer tomography finding revealed multilocular intrabony lesion with radiopaque substance in the primary lesion. In the recurrent lesion cortical bone destruction was found. Microscopically, both the primary and recurrent lesions showed benign ameloblastic follicles with myxoid or highly cellular mesenchymal proliferation. The histological difference between primary and recurrent lesions were that foci of dental hard tissue composed of enamel and dentin were found only in the primary lesion, whereas nuclear pleomorphism was aggrevated in the recurrent lesion. The histological criteria determining malignancy were discussed.
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T201702279.pdf Download
DOI
10.17779/KAOMP.2017.41.1.006
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
김진(Kim, Jin)
김현실(Kim, Hyun Sil) ORCID logo https://orcid.org/0000-0003-3614-1764
남웅(Nam, Woong) ORCID logo https://orcid.org/0000-0003-0146-3624
육종인(Yook, Jong In) ORCID logo https://orcid.org/0000-0002-7318-6112
조은애산드라(Cho, Eunae) ORCID logo https://orcid.org/0000-0002-0820-3019
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160391
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