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Protein-Losing Enteropathy as a Complication of the Ketogenic Diet.

Authors
 Won Kee Ahn  ;  Soyoung Park  ;  Heung Dong Kim 
Citation
 Yonsei Medical Journal, Vol.58(4) : 891-893, 2017 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2017
MeSH
Diet, Ketogenic/adverse effects* ; Duodenum/pathology ; Humans ; Infant ; Male ; Mucous Membrane/pathology ; Nutritional Support ; Protein-Losing Enteropathies/complications*
Keywords
Ketogenic diet ; hypoalbuminemia ; protein-losing enteropathies
Abstract
The ketogenic diet is an effective treatment for the patients with intractable epilepsy, however, the diet therapy can sometimes be discontinued by complications. Protein-losing enteropathy is a rarely reported serious complication of the ketogenic diet. We present a 16-month-old Down syndrome baby with protein-losing enteropathy during the ketogenic diet as a treatment for West syndrome. He suffered from diarrhea, general edema and hypoalbuminemia which were not controlled by conservative care for over 1 month. Esophagogastroduodenoscopy and stool alpha-1 antitrypsin indicated protein-losing enteropathy. Related symptoms were relieved after cessation of the ketogenic diet. Unexplained hypoalbuminemia combined with edema and diarrhea during ketogenic suggests the possibility of protein-losing enteropathy, and proper evaluation is recommended in order to expeditiously detect it and to act accordingly.
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DOI
10.3349/ymj.2017.58.4.891
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Heung Dong(김흥동) ORCID logo https://orcid.org/0000-0002-8031-7336
Ahn, Won Kee(안원기)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160248
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