102 93

Cited 7 times in

Community-onset extended-spectrum-β-lactamase-producing Escherichia coli sequence type 131 at two Korean community hospitals: The spread of multidrug-resistant E. coli to the community via healthcare facilities

Authors
 Young Ah Kim  ;  Jin Ju Kim  ;  Heejung Kim  ;  Kyungwon Lee 
Citation
 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, Vol.54 : 39-42, 2017 
Journal Title
 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 
ISSN
 1201-9712 
Issue Date
2017
MeSH
Anti-Bacterial Agents/pharmacology ; Drug Resistance, Multiple, Bacterial* ; Escherichia coli/drug effects* ; Escherichia coli/enzymology* ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/microbiology* ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism* ; Female ; Hospitals, Community ; Humans ; Male ; Middle Aged ; Molecular Epidemiology ; Prevalence ; Prospective Studies ; Republic of Korea/epidemiology ; Urinary Tract Infections/epidemiology ; Urinary Tract Infections/microbiology ; beta-Lactamases/genetics ; beta-Lactamases/metabolism*
Keywords
Community-onset infection ; Escherichia coli ; Extended-Spectrum-β-Lactamase ; Sequence type 131
Abstract
BACKGROUND: The recent molecular epidemiology of ESBL-producing Escherichia coli infection in two Korean community hospitals was evaluated in this prospective observational study. METHODS: We collected non-duplicated E. coli isolates from consecutive, sequentially encountered patients with community-onset episodes between March and April 2016 in two community hospitals in Gyeonggi-do province, Korea. We studied the prevalence, clinical characteristics and molecular epidemiology of E. coli sequence type 131 (ST131) isolated from the community. RESULTS: From a total of 213 E. coli isolates collected from the community, 94 (44.1%) were community-onset healthcare-associated isolates and 119 (55.9%) were community-associated isolates, of which urinary tract infection was the majority. A total of 55 (25.8%) of the 213 E. coli isolates were confirmed to have ESBL genes, which were mainly CTX-M types such as CTX-M-14 and CTX-M-15. There was no difference in the proportion of globally epidemic ST131 clones or that of O25, O16, H30, or H30Rx subclones between community-associated and community-onset healthcare-associated isolates. CONCLUSIONS: In this study, considerable ST131 E. coli isolations in the community were observed and about half of them were related to the history of a visit to the healthcare facilities, indicating the spread of multidrug-resistant E. coli to the community via healthcare facilities.
Files in This Item:
T201700020.pdf Download
DOI
10.1016/j.ijid.2016.11.010
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Heejung(김희정) ORCID logo https://orcid.org/0000-0002-0190-703X
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160195
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse