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A case of acute polyneuropathy with nephrotic syndrome showing transient proximal sensory conduction defects

Authors
 Jeeyoung Oh  ;  Seung-Min Kim  ;  Il Nam Sunwoo 
Citation
 YONSEI MEDICAL JOURNAL, Vol.53(2) : 446-449, 2012 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2012
MeSH
Evoked Potentials, Somatosensory/physiology ; Humans ; Male ; Middle Aged ; Nephrotic Syndrome/diagnosis* ; Nephrotic Syndrome/physiopathology* ; Polyneuropathies/diagnosis* ; Polyneuropathies/physiopathology*
Abstract
Acute sensorimotor polyneuropathy that resembles Guillain-Barré syndrome (GBS) is rarely accompanied with nephrotic syndrome, and its underlying immunological mechanisms are unclear. A 56-year-old man presented with simultaneous acute progressive symmetric sensorimotor polyneuropathy and proteinuria. A kidney biopsy revealed focal segmental glomerulosclerosis. Serial electrophysiologic studies showed only a transient proximal conduction block in the median nerve, stimulated somatosensory evoked potential and prolonged terminal latencies of the median and peroneal nerves. The patient's neurologic deficits and kidney dysfunction recovered with corticosteroid treatment. Our case showed that somatosensory evoked potential study can be an important objective tool in the diagnosis of acute polyneuropathy with normal distal nerve conduction and that corticosteroids should be considered in the initial treatment of GBS-resembling polyneuropathy associated with nephrotic syndrome.
Files in This Item:
T201206307.pdf Download
DOI
10.3349/ymj.2012.53.2.446
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Min(김승민) ORCID logo https://orcid.org/0000-0002-4384-9640
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158307
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