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Two cases of Wernicke's encephalopathy in young age patients receiving allogeneic hematopoietic stem cell transplantation

Authors
 Jung Woo Han  ;  Seungtaek Lim  ;  Hye Sun Shin  ;  Hee Jin Park  ;  Won Jai Jung  ;  Seung Yeon Kwon  ;  Chuhl Joo Lyu 
Citation
 Yonsei Medical Journal, Vol.53(5) : 1049-1053, 2012 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2012
MeSH
Child ; Hematopoietic Stem Cell Transplantation* ; Humans ; Male ; Thiamine/therapeutic use ; Transplantation, Homologous* ; Wernicke Encephalopathy/drug therapy ; Wernicke Encephalopathy/therapy*
Abstract
Wernicke's encephalopathy is an acute neurolopsychiatric syndrome caused by thiamine deficiency, and classically presents with the triad of opthalmopathy, ataxia and altered mentality. Both prolonged total parenteral nutrition and reduced oral intake can induce Wernicke's encephalopathy during hematopoietic stem cell transplantation (HSCT). Although early treatment is important for recovery from Wernicke's encephalopathy, the vague symptoms and characteristics hinder early diagnosis. Furthermore, Wernicke's encephalopathy is not infrequent and can develop at any age during HSCT. Herein, we present two young patients developing Wernicke's encephalopathy during HSCT.
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DOI
10.3349/ymj.2012.53.5.1049
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
권승연(Kwon, Seung Yeon)
박효진(Park, Hyo Jin) ORCID logo https://orcid.org/0000-0003-4814-8330
유철주(Lyu, Chuhl Joo) ORCID logo https://orcid.org/0000-0001-7124-7818
임승택(Lim, Seung Taek)
한정우(Han, Jung Woo) ORCID logo https://orcid.org/0000-0001-8936-1205
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158282
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