50세 이상의 한국인에서 25-하이드록시 비타민 D, 부갑상선호르몬과 이상지질혈증과의 관련성: 국민건강영양조사 자료 활용 2011

Abstract

Background: In this study, we investigated the relation of serum 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) concentrations with the risk of dyslipidemia in Korean adults aged 50 years and older, by using the most recent available Korean National Health and Nutrition Examination Surveys data.

Methods: The sample of this population-based cross-sectional study consisted of 467 Korean adults who participated in the fifth Korean National Health and Nutrition Examination Surveys conducted in 2011. Participants who were taking lipid medications were excluded. Serum 25(OH)D concentrations were measured with radioimmunoassay, and serum PTH concentrations were measured with chemiluminescence assay.

Results: The median concentrations of serum 25(OH)D and PTH for the entire group were 17.25 ng/mL and 65.07 pg/mL, respectively. In logistic regression analyses, the serum 25(OH)D and PTH concentrations were not significantly associated with the risk of dyslipidemia after adjustment for age, region, income, education level, smoking status, alcohol intake, and physical activity (p > 0.05).

Conclusion: Serum 25(OH)D and PTH concentrations are not independently associated with serum lipid levels or an increased risk of dyslipidemia in the Korean population ≥ 50 years.