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수축기혈압이 위팔-발목 맥파전파속도와 목동맥-넙다리동맥 맥파전파속도 간의 결과불일치에 미치는 영향

Other Titles
 The Influence of Systolic Blood Pressure on Discordance between Brachial-Ankle Pulse Wave Velocity and Carotid-Femoral Pulse Wave Velocity Results 
 한민호  ;  진복희  ;  허지회  ;  이용흠 
 Journal of Neurosonology (신경초음파학회지), Vol.7(1) : 6-13, 2015 
Journal Title
 Journal of Neurosonology (신경초음파학회지) 
Issue Date
Background: The brachial-ankle pulse wave velocity (baPWV) is more likely to be influenced by high blood pressure than carotid-femoral pulse wave velocity (cfPWV), since baPWV includes some peripheral arterial components, which have less cushioning against high pressure than central arteries, in addition to central arterial components. So, it is feared that reliability of baPWV will decline in patients with high systolic blood pressure (SBP). Methods: We studied 114 patients with acute brain infarction or transient ischemic attack who underwent both baPWV and cfPWV measurements. We investigated the influence of SBP on discordance between baPWV and cfPWV results in patients with a slightly high SBP. Results: 114 patients were divided into accordance and discordance groups by matching both pulse wave velocity (PWV) results. The percentage of an abnormal cfPWV was higher in the accordance group (p<0.001). However, the percentage of an abnormal baPWV was higher in the discordance group (p=0.001). The brachial artery systolic blood pressure (bSBP) was categorized into two groups (<144 mmHg bSBP, and ≥144 mmHg bSBP) based on 144 mmHg bSBP. The central artery systolic blood pressure (cSBP) also was categorized into two groups (<133 mmHg cSBP, and ≥133 mmHg cSBP) based on 133 mmHg cSBP. In multivariate analysis, after adjusting for confounding factors, <144 mmHg bSBP was independently associated with the discordance of PWV findings (p=0.037). However, <133 mmHg cSBP was not associated with the discordance of PWV findings. Conclusions: It was found that baPWV was more affected by bSBP, and resulted in an abnormal finding in spite of a normal finding of the cfPWV measurement in the same subject with <144 mmHg bSBP. Our study suggests that cfPWV is more useful than baPWV to estimate the arterial stiffness in patients with a slightly higher bSBP.
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
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