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Acute Respiratory Distress Syndrome after the Use of Gadolinium Contrast Media

 Jihye Park  ;  Il Hwan Byun  ;  Kyung Hee Park  ;  Jae-Hyun Lee  ;  Eun Ji Nam  ;  Jung-Won Park 
 YONSEI MEDICAL JOURNAL, Vol.56(4) : 1155-1157, 2015 
Journal Title
Issue Date
Adult ; Animals ; Contrast Media/administration & dosage ; Contrast Media/adverse effects* ; Female ; Gadolinium ; Humans ; Magnetic Resonance Imaging/methods* ; Organometallic Compounds*/adverse effects ; Respiratory Distress Syndrome, Adult/chemically induced* ; Tomography, X-Ray Computed
Gadolinium ; acute respiratory distress syndrome ; gadobutrol
Acute respiratory distress syndrome (ARDS) is a medical emergency that threatens life. To this day, ARDS is very rarely reported by iodine contrast media, and there is no reported case of ARDS induced by gadolinium contrast media. Here, we present a case with ARDS after the use of gadobutrol (Gadovist) as a magnetic resonance imaging (MRI) contrast medium. A 26 years old female without any medical history, including allergic diseases and without current use of drugs, visited the emergency room for abdominal pain. Her abdominopelvic computed tomography with iodine contrast media showed a right ovarian cyst and possible infective colitis. Eighty-three hours later, she underwent pelvis MRI after injection of 7.5 mL (0.1 mL/kg body weight) of gadobutrol (Gadovist) to evaluate the ovarian cyst. She soon presented respiratory difficulty, edema of the lips, nausea, and vomiting, and we could hear wheezing upon auscultation. She was treated with dexamethasone, epinephrine, and norepinephrine. Her chest X-ray showed bilateral central bat-wing consolidative appearance. Managed with mechanical ventilation, she was extubated 3 days later and discharged without complications.
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Nam, Eun Ji(남은지) ORCID logo https://orcid.org/0000-0003-0189-3560
Park, Kyung Hee(박경희) ORCID logo https://orcid.org/0000-0003-3605-5364
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Park, Ji Hye(박지혜)
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
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