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Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea

Authors
 June-Hee Lee  ;  Inah Kim  ;  Hongdeok Seok  ;  Inhyo Park  ;  Jungho Hwang  ;  Jae-Oh Park  ;  Jong-Uk Won  ;  Jaehoon Roh 
Citation
 ANNALS OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol.27(19) : 1-5, 2015 
Journal Title
 ANNALS OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 
Issue Date
2015
Keywords
Automobiles ; Carcinoma ; Korea ; Occupational disease ; Renal cell ; Trichloroethylene
Abstract
BACKGROUND: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea. CASE PRESENTATION: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction. CONCLUSIONS: From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.
Files in This Item:
T201504724.pdf Download
DOI
10.1186/s40557-015-0068-x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Roh, Jae Hoon(노재훈)
Seok, Hongdeok(석홍덕)
Won, Jong Uk(원종욱) ORCID logo https://orcid.org/0000-0002-9200-3297
Lee, June Hee(이준희)
Hwang, Jung Ho(황정호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/156813
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