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Stents with specialized functions: drug-eluting stents and stents with antireflux devices

Authors
 Sung Ill Jang  ;  Dong Ki Lee 
Citation
 Gastrointestinal Intervention, Vol.4(1) : 50-54, 2015 
Journal Title
 Gastrointestinal Intervention 
Issue Date
2015
Keywords
antireflux stent ; drug-eluting stent ; functional stent ; malignant biliary obstruction
Abstract
Biliary drainage in malignant biliary obstruction improves patient survival and quality of life. Although bypass surgery was historically the main method of treating malignant biliary obstruction, stent insertion using endoscopy or interventional radiology is currently recognized as the first-line of treatment. Biliary stents have undergone various modifications in terms of material and structure, with the aim of increasing stent patency. One such modification is the antitumor-agent-eluting stent, which is intended to suppress tumor ingrowth through chemical changes in the membrane. Another modified stent is the antireflux stent, which physically prevents the reflux of food by using an antireflux valve. Although the safety of these modified stents has been demonstrated in both animal and human studies, their efficacy, compared with conventional stents, remains unknown. Although the development of these functional stents is challenging, their potential is promising. Effort is necessary to increase stent patency, which requires much modification and development, to prolong patient survival.
Full Text
http://www.sciencedirect.com/science/article/pii/S2213179515000103
DOI
10.1016/j.gii.2015.03.004
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Dong Ki(이동기) ORCID logo https://orcid.org/0000-0002-0048-9112
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/155723
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