우리나라 18세 이상 성인에서 수면시간의 길이와 골밀도와의 관련성: 국민건강영양조사 자료 활용 2010

Abstract

Background: Sleep duration is associated with many diseases, yet few studies have been performed on the association between sleep duration and bone mineral density(BMD) in Korea. In this study we investigated the association between sleep duration and bone mineral density in adults over 18 years of age. Methods: Subjects of this study were adults over 18 years of age who responded to a questionnaire on sleep duration and underwent BMD measurement by dual X-ray absorptiometry. Comprehensive data on the study sample was obtained from the Korean National Health and Nutrition Examination Survey(KHANES) conducted in 2010. Age- and sex-stratified multiple regression analyses were conducted with adjustment for possible confounding factors. Results: There was an inverse, dose-dependent association between sleep duration and BMD measured in the total femur, femur neck, lumbar spine and total bone in both women over 50 years of age and men between 30 and 49 years of age. Sex-stratified multiple regression analysis adjusted for age and body mass index revealed a negative correlation between sleep duration and BMD in the total femur and femur neck in both genders over 50 years of age, as well as in women between ages 30 and 49. Initial significance disappeared after adjustment for additional covariates including smoking, alcohol, and exercise. Conclusion: Significant variations in regional BMD with sleep duration were observed among women and men between ages 30 and 49. Prolonged sleep duration appears to be a risk factor for low bone mineral density. Thus, adequate sleep duration is important for preventing osteoporosis