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Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects
DC Field | Value | Language |
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dc.contributor.author | 이지원 | - |
dc.date.accessioned | 2018-01-23T05:48:50Z | - |
dc.date.available | 2018-01-23T05:48:50Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0960-8923 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/155659 | - |
dc.description.abstract | The effect of consumption of two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, on weight loss, body adiposity and lipoprotein-associated phospholipase A2 (Lp-PLA2) activities in overweight subjects was examined. After 12-week probiotic treatment, the probiotic group presented reductions in body weight (−0.65 ± 0.23 kg), body fat percentage (−0.57 ± 0.19%) and body fat mass (−616 ± 161 g) measured using DEXA, and L1 subcutaneous fat area (−2.68 ± 1.31 cm2) measured using CT, compared to baseline. The probiotic group exhibited greater reductions in oxidized low density lipoprotein (ox-LDL) (P < 0.001) and Lp-PLA2 (P < 0.001) and a greater increase in low density lipoprotein (LDL) particle size (P = 0.001) than the placebo. The change (△, difference from baseline) in total fat mass correlated with △ Lp-PLA2 (r = 0.480, P < 0.001), which correlated with △ ox-LDL (r = 0.537, P < 0.001). Probiotic-induced weight loss was associated with reductions in fat mass, which correlated with the changes in Lp-PLA2 activities (ClinicalTrials.gov: NCT02492698). | - |
dc.description.statementOfResponsibility | restriction | - |
dc.relation.isPartOf | OBESITY SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Family Medicine | - |
dc.contributor.googleauthor | Saem Jung | - |
dc.contributor.googleauthor | Young Ju Lee | - |
dc.contributor.googleauthor | Minkyung Kim | - |
dc.contributor.googleauthor | Minjoo Kim | - |
dc.contributor.googleauthor | Jung Hyun Kwak | - |
dc.contributor.googleauthor | Ji-Won Lee | - |
dc.contributor.googleauthor | Young-Tae Ahn | - |
dc.contributor.googleauthor | Jae-Hun Sim | - |
dc.contributor.googleauthor | Jong Ho Lee | - |
dc.identifier.doi | 10.1016/j.jff.2015.10.006 | - |
dc.contributor.localId | A03203 | - |
dc.relation.journalcode | J02888 | - |
dc.identifier.eissn | 1708-0428 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1756464615005034 | - |
dc.subject.keyword | Probiotic | - |
dc.subject.keyword | Weight loss | - |
dc.subject.keyword | Fat mass | - |
dc.subject.keyword | Lp-PLA2 | - |
dc.subject.keyword | CT | - |
dc.subject.keyword | DEXA | - |
dc.contributor.alternativeName | Lee, Ji Won | - |
dc.contributor.affiliatedAuthor | Lee, Ji Won | - |
dc.citation.volume | 19 | - |
dc.citation.number | Part A | - |
dc.citation.startPage | 744 | - |
dc.citation.endPage | 752 | - |
dc.identifier.bibliographicCitation | OBESITY SURGERY, Vol.19(Part A) : 744-752, 2015 | - |
dc.identifier.rimsid | 48123 | - |
dc.type.rims | ART | - |
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