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Characteristics of Atopic Dermatitis in a Post-childhood Atopic March Group

Authors
 Hemin Lee  ;  Jung U Shin  ;  Jungsoo Lee  ;  Howard Chu  ;  Kwang Hoon Lee 
Citation
 Korean Journal of Dermatology (대한피부과학회지), Vol.55(2) : 110-115, 2017 
Journal Title
 Korean Journal of Dermatology (대한피부과학회지) 
ISSN
 0494-4739 
Issue Date
2017
Keywords
Atopic dermatitis ; Atopic march ; Allergic march ; Dust mite
Abstract
BACKGROUND: Little knowledge is available on the characteristic differences between patients with atopic dermatitis (AD) with and without atopic march after childhood. OBJECTIVE: To observe and compare the phenotypes of patients with AD in regards to atopic march tendency at a single point. METHODS: We enrolled patients with AD aged between 10 and 30 years. The patients were divided into the atopic march and non-atopic march groups on the basis of an investigator-designed survey questionnaire, and their serum-specific immunoglobulin E (IgE) levels or results of the skin prick test were compared. RESULTS: In a total of 182 patients enrolled in the study, 93 patients with atopic march and 89 patients with non-atopic march were observed. When their serum-specific IgE levels or results of the skin prick test were compared between the two groups, there was no significant difference, except for a in the atopic march group. Analysis of AD severity, family history of allergic diseases, and total IgE levels between the two groups showed no statistically significant differences. CONCLUSION: Our findings suggest that although no apparent phenotype characteristics could differentiate the presence of atopic march, the history of the patient's allergic diseases should be revalidated, and clinicians should watch out for future developments of atopic march when a patient shows a high-class sensitization rate to dust mite.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jung U(신정우) ORCID logo https://orcid.org/0000-0001-5259-6879
Lee, Kwang Hoon(이광훈)
Lee, Jungsoo(이정수)
Lee, Hemin(이혜민)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154661
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