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Common causes of postmenopausal bleeding in Korean women: 10-year outcomes from a single medical center

 Min Kyoung Kim  ;  Yeon Soo Jung  ;  Seung Joo Chon  ;  Bo Hyon Yun  ;  SiHyun Cho  ;  Young Sik Choi  ;  Byung Seok Lee  ;  Seok Kyo Seo 
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.32(5) : 830-834, 2017 
Journal Title
Issue Date
Anticoagulants/adverse effects ; Anticoagulants/therapeutic use ; Atrophy/complications ; Atrophy/epidemiology* ; Endometrial Neoplasms/complications ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/epidemiology ; Female ; Hemorrhage/etiology* ; Hormone Replacement Therapy/adverse effects ; Humans ; Middle Aged ; Postmenopause ; Republic of Korea/epidemiology ; Retrospective Studies ; Uterine Cervical Neoplasms/complications ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/epidemiology
Common Cause of Postmenopausal Bleeding ; Hormone Replacement Therapy ; Korean Postmenopausal Women ; Postmenopausal Bleeding
The common causes of postmenopausal bleeding (PMB), according to the data from the western world, are atrophy, hormone replacement therapy (HRT), endometrial cancer, etc. We conducted a retrospective study to assess whether the causes of PMB in Korean postmenopausal women are similar to those already known. This retrospective study used 10-year medical records (March 2005 to December 2014) of 792 PMB women in the Yonsei University Health System. The data were divided into 2 categories by 5-year intervals to compare the differences between the 2 periods. The most common cause of PMB in Korean women was atrophy (51.1%). Polyps and HRT were the second, followed by anticoagulant medications, cervical cancer, and endometrial cancer. The proportion of patients with cervical cancer significantly decreased during the second half of the decade (8.7% vs. 5.2%; P = 0.048). Although no significant change was noted for HRT, its rank was higher during the latter 5-year period. Only the most common cause of PMB was the same as the conventional data. Interestingly, the proportion of patients with cervical cancer decreased during the latter half of the decade, reflecting the changes in the nation's cancer prevalence rate, while the use of HRT increased.
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min Kyoung(김민경)
Seo, Seok Kyo(서석교) ORCID logo https://orcid.org/0000-0003-3404-0484
Yun, Bo Hyon(윤보현) ORCID logo https://orcid.org/0000-0001-5703-797X
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
Cho, Si Hyun(조시현) ORCID logo https://orcid.org/0000-0003-2718-6645
Choi, Young Sik(최영식) ORCID logo https://orcid.org/0000-0002-1157-4822
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