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Correlation of Serum Creatine Kinase Level With Pulmonary Function in Duchenne Muscular Dystrophy
DC Field | Value | Language |
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dc.contributor.author | 강성웅 | - |
dc.contributor.author | 서미리 | - |
dc.contributor.author | 오현준 | - |
dc.contributor.author | 최원아 | - |
dc.contributor.author | 김은영 | - |
dc.date.accessioned | 2017-11-02T08:21:06Z | - |
dc.date.available | 2017-11-02T08:21:06Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2234-0645 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/154368 | - |
dc.description.abstract | OBJECTIVE: To investigate the relationship between serum creatine kinase (CK) level and pulmonary function in Duchenne muscular dystrophy (DMD). METHODS: A total of 202 patients with DMD admitted to the Department of Rehabilitation Medicine, Gangnam Severance Hospital were enrolled from January 1, 1999 to March 31, 2015. Seventeen patients were excluded. Data collected from the 185 patients included age, height, weight, body mass index, pulmonary function tests including forced vital capacity (FVC), peak cough flow, maximal expiratory pressure (MEP), and maximal inspiratory pressure (MIP), and laboratory measurements (serum level of CK, CK-MB, troponin-T, and B-type natriuretic peptide). FVC, MEP, and MIP were expressed as percentages of predicted normal values. RESULTS: Serum CK activities were elevated above normal levels, even in the oldest DMD group. Serum CK level was strongly correlated with pulmonary functions of sitting FVC (p<0.001), supine FVC (p<0.001), MIP (p=0.004), and MEP (p<0.001). CONCLUSION: Serum CK level is a reliable screening test even in patients with advanced DMD, and is a strong predictor of pulmonary functions. | - |
dc.description.statementOfResponsibility | open | - |
dc.publisher | Korean Academy of Rehabilitation Medicine | - |
dc.relation.isPartOf | Annals of Rehabilitation Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Correlation of Serum Creatine Kinase Level With Pulmonary Function in Duchenne Muscular Dystrophy | - |
dc.title.alternative | 뒤시엔느 근디스트로피 환자에서 혈청 크레아틴 키나아제 수준과 호흡 기능과의 연관성 | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Rehabilitation Medicine | - |
dc.contributor.googleauthor | Eun Young Kim | - |
dc.contributor.googleauthor | Jang Woo Lee | - |
dc.contributor.googleauthor | Mi Ri Suh | - |
dc.contributor.googleauthor | Won Ah Choi | - |
dc.contributor.googleauthor | Seong Woong Kang | - |
dc.contributor.googleauthor | Hyeon Jun Oh | - |
dc.identifier.doi | 10.5535/arm.2017.31.2.306 | - |
dc.contributor.localId | A04582 | - |
dc.contributor.localId | A04607 | - |
dc.contributor.localId | A04125 | - |
dc.contributor.localId | A05101 | - |
dc.contributor.localId | A00041 | - |
dc.relation.journalcode | J00177 | - |
dc.relation.journalsince | 2011~ | - |
dc.identifier.pmid | 28503465 | - |
dc.relation.journalbefore | ~2011 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지) | - |
dc.subject.keyword | Creatine kinase | - |
dc.subject.keyword | Duchenne muscular dystrophy | - |
dc.subject.keyword | Respiratory function tests | - |
dc.contributor.alternativeName | Kang, Seong Woong | - |
dc.contributor.alternativeName | Suh, Mi Ri | - |
dc.contributor.alternativeName | Oh, Hyeon Jun | - |
dc.contributor.alternativeName | Choi, Won Ah | - |
dc.contributor.alternativeName | Kim, Eun Young | - |
dc.contributor.affiliatedAuthor | Suh, Mi Ri | - |
dc.contributor.affiliatedAuthor | Oh, Hyeon Jun | - |
dc.contributor.affiliatedAuthor | Choi, Won Ah | - |
dc.contributor.affiliatedAuthor | Kim, Eun Young | - |
dc.contributor.affiliatedAuthor | Kang, Seong Woong | - |
dc.citation.title | Annals of Rehabilitation Medicine | - |
dc.citation.volume | 41 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 306 | - |
dc.citation.endPage | 312 | - |
dc.identifier.bibliographicCitation | Annals of Rehabilitation Medicine, Vol.41(2) : 306-312, 2017 | - |
dc.date.modified | 2017-11-01 | - |
dc.identifier.rimsid | 42938 | - |
dc.type.rims | ART | - |
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