244 339

Cited 3 times in

Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits

DC Field Value Language
dc.contributor.author정의원-
dc.contributor.author차재국-
dc.contributor.author최성호-
dc.date.accessioned2017-11-02T08:21:03Z-
dc.date.available2017-11-02T08:21:03Z-
dc.date.issued2017-
dc.identifier.issn2093-2278-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154367-
dc.description.abstractPURPOSE: The aim of this study was to determine the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2)-loaded synthetic bone substitute on implants that were simultaneously placed with sinus augmentation in rabbits. METHODS: In this study, a circular access window was prepared in the maxillary sinus of rabbits (n=5) for a bone graft around an implant (Ø 3×6 mm) that was simultaneously placed anterior to the window. Synthetic bone substitute loaded with rhBMP-2 was placed on one side of the sinus to form the experimental group, and saline-soaked synthetic bone substitute was placed on the other side of the sinus to form the control group. After 4 weeks, sections were obtained for analysis by micro-computed tomography and histology. RESULTS: Volumetric analysis showed that the median amount of newly formed bone was significantly greater in the BMP group than in the control group (51.6 mm3 and 46.6 mm3, respectively; P=0.019). In the histometric analysis, the osseointegration height was also significantly greater in the BMP group at the medial surface of the implant (5.2 mm and 4.3 mm, respectively; P=0.037). CONCLUSIONS: In conclusion, an implant simultaneously placed with sinus augmentation using rhBMP-2-loaded synthetic bone substitute can be successfully osseointegrated, even when only a limited bone height is available during the early stage of healing.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Academy of Periodontology-
dc.relation.isPartOfJOURNAL OF PERIODONTAL AND IMPLANT SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Dentistry-
dc.contributor.departmentDept. of Periodontology-
dc.contributor.googleauthorMyung-Jae Joo-
dc.contributor.googleauthorJae-Kook Cha-
dc.contributor.googleauthorHyun-Chang Lim-
dc.contributor.googleauthorSeong-Ho Choi-
dc.contributor.googleauthorUi-Won Jung-
dc.identifier.doi10.5051/jpis.2017.47.2.86-
dc.contributor.localIdA04004-
dc.contributor.localIdA04081-
dc.contributor.localIdA03692-
dc.relation.journalcodeJ01695-
dc.identifier.eissn2093-2286-
dc.relation.journalsince2010~-
dc.identifier.pmid28462007-
dc.relation.journalbefore~2009 Journal of Korean Academy of Periodontology (대한치주과학회지)-
dc.subject.keywordBone substitutes-
dc.subject.keywordCollagen-
dc.subject.keywordDental implants-
dc.subject.keywordRecombinant human bone morphogenetic protein-2-
dc.subject.keywordSinus floor augmentation-
dc.contributor.alternativeNameJung, Ui Won-
dc.contributor.alternativeNameCha, Jae Kook-
dc.contributor.alternativeNameChoi, Seong Ho-
dc.contributor.affiliatedAuthorCha, Jae Kook-
dc.contributor.affiliatedAuthorChoi, Seong Ho-
dc.contributor.affiliatedAuthorJung, Ui Won-
dc.citation.titleJournal of Periodontal & Implant Science-
dc.citation.volume47-
dc.citation.number2-
dc.citation.startPage86-
dc.citation.endPage95-
dc.identifier.bibliographicCitationJOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, Vol.47(2) : 86-95, 2017-
dc.date.modified2017-11-01-
dc.identifier.rimsid42937-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.