Cited 8 times in
Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits
DC Field | Value | Language |
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dc.contributor.author | 정의원 | - |
dc.contributor.author | 차재국 | - |
dc.contributor.author | 최성호 | - |
dc.date.accessioned | 2017-11-02T08:21:03Z | - |
dc.date.available | 2017-11-02T08:21:03Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2093-2278 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/154367 | - |
dc.description.abstract | PURPOSE: The aim of this study was to determine the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2)-loaded synthetic bone substitute on implants that were simultaneously placed with sinus augmentation in rabbits. METHODS: In this study, a circular access window was prepared in the maxillary sinus of rabbits (n=5) for a bone graft around an implant (Ø 3×6 mm) that was simultaneously placed anterior to the window. Synthetic bone substitute loaded with rhBMP-2 was placed on one side of the sinus to form the experimental group, and saline-soaked synthetic bone substitute was placed on the other side of the sinus to form the control group. After 4 weeks, sections were obtained for analysis by micro-computed tomography and histology. RESULTS: Volumetric analysis showed that the median amount of newly formed bone was significantly greater in the BMP group than in the control group (51.6 mm3 and 46.6 mm3, respectively; P=0.019). In the histometric analysis, the osseointegration height was also significantly greater in the BMP group at the medial surface of the implant (5.2 mm and 4.3 mm, respectively; P=0.037). CONCLUSIONS: In conclusion, an implant simultaneously placed with sinus augmentation using rhBMP-2-loaded synthetic bone substitute can be successfully osseointegrated, even when only a limited bone height is available during the early stage of healing. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Academy of Periodontology | - |
dc.relation.isPartOf | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Dentistry | - |
dc.contributor.department | Dept. of Periodontology | - |
dc.contributor.googleauthor | Myung-Jae Joo | - |
dc.contributor.googleauthor | Jae-Kook Cha | - |
dc.contributor.googleauthor | Hyun-Chang Lim | - |
dc.contributor.googleauthor | Seong-Ho Choi | - |
dc.contributor.googleauthor | Ui-Won Jung | - |
dc.identifier.doi | 10.5051/jpis.2017.47.2.86 | - |
dc.contributor.localId | A04004 | - |
dc.contributor.localId | A04081 | - |
dc.contributor.localId | A03692 | - |
dc.relation.journalcode | J01695 | - |
dc.identifier.eissn | 2093-2286 | - |
dc.relation.journalsince | 2010~ | - |
dc.identifier.pmid | 28462007 | - |
dc.relation.journalbefore | ~2009 Journal of Korean Academy of Periodontology (대한치주과학회지) | - |
dc.subject.keyword | Bone substitutes | - |
dc.subject.keyword | Collagen | - |
dc.subject.keyword | Dental implants | - |
dc.subject.keyword | Recombinant human bone morphogenetic protein-2 | - |
dc.subject.keyword | Sinus floor augmentation | - |
dc.contributor.alternativeName | Jung, Ui Won | - |
dc.contributor.alternativeName | Cha, Jae Kook | - |
dc.contributor.alternativeName | Choi, Seong Ho | - |
dc.contributor.affiliatedAuthor | Cha, Jae Kook | - |
dc.contributor.affiliatedAuthor | Choi, Seong Ho | - |
dc.contributor.affiliatedAuthor | Jung, Ui Won | - |
dc.citation.title | Journal of Periodontal & Implant Science | - |
dc.citation.volume | 47 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 86 | - |
dc.citation.endPage | 95 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, Vol.47(2) : 86-95, 2017 | - |
dc.date.modified | 2017-11-01 | - |
dc.identifier.rimsid | 42937 | - |
dc.type.rims | ART | - |
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