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Human Coronavirus in the 2014 Winter Season as a Cause of Lower Respiratory Tract Infection

DC FieldValueLanguage
dc.contributor.author김규연-
dc.contributor.author김동수-
dc.contributor.author김호성-
dc.contributor.author한송이-
dc.date.accessioned2017-11-02T08:11:06Z-
dc.date.available2017-11-02T08:11:06Z-
dc.date.issued2017-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154173-
dc.description.abstractPURPOSE: During the late autumn to winter season (October to December) in the Republic of Korea, respiratory syncytial virus (RSV) is the most common pathogen causing lower respiratory tract infections (LRTIs). Interestingly, in 2014, human coronavirus (HCoV) caused not only upper respiratory infections but also LRTIs more commonly than in other years. Therefore, we sought to determine the epidemiology, clinical characteristics, outcomes, and severity of illnesses associated with HCoV infections at a single center in Korea. MATERIALS AND METHODS: We retrospectively identified patients with positive HCoV respiratory specimens between October 2014 and December 2014 who were admitted to Severance Children's Hospital at Yonsei University Medical Center for LRTI. Charts of the patients with HCoV infection were reviewed and compared with RSV infection. RESULTS: During the study period, HCoV was the third most common respiratory virus and accounted for 13.7% of infections. Coinfection was detected in 43.8% of children with HCoV. Interestingly, one patient had both HCoV-OC43 and HCoV-NL63. Mild pneumonia was most common (60.4%) with HCoV, and when combined with RSV, resulted in bronchiolitis. Two patients required care in the intensive care unit. However, compared with that of RSV infection, the disease course HCoV was short. CONCLUSION: Infections caused by HCoVs are common, and can cause LRTIs. During an epidemic season, clinicians should be given special consideration thereto. When combined with other medical conditions, such as neurologic or cardiologic diseases, intensive care unit (ICU) care may be necessary.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHCoronavirus/isolation & purification*-
dc.subject.MESHCoronavirus Infections/epidemiology-
dc.subject.MESHCoronavirus Infections/virology*-
dc.subject.MESHCoronavirus OC43, Human/isolation & purification-
dc.subject.MESHFemale-
dc.subject.MESHHospitalization-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRespiratory Tract Infections/epidemiology-
dc.subject.MESHRespiratory Tract Infections/virology*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSeasons-
dc.titleHuman Coronavirus in the 2014 Winter Season as a Cause of Lower Respiratory Tract Infection-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorKyu Yeun Kim-
dc.contributor.googleauthorSong Yi Han-
dc.contributor.googleauthorHo-Seong Kim-
dc.contributor.googleauthorHyang-Min Cheong-
dc.contributor.googleauthorSung Soon Kim-
dc.contributor.googleauthorDong Soo Kim-
dc.identifier.doi10.3349/ymj.2017.58.1.174-
dc.contributor.localIdA00405-
dc.contributor.localIdA01184-
dc.contributor.localIdA04699-
dc.contributor.localIdA04514-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid27873511-
dc.subject.keywordCoronavirus-
dc.subject.keywordchildren-
dc.subject.keywordclinical severity-
dc.subject.keywordrespiratory syncytial virus-
dc.subject.keywordrespiratory viruses-
dc.contributor.alternativeNameKim, Kyu Yeun-
dc.contributor.alternativeNameKim, Dong Soo-
dc.contributor.alternativeNameKim, Ho Seong-
dc.contributor.alternativeNameHan, Song Yi-
dc.contributor.affiliatedAuthorKim, Dong Soo-
dc.contributor.affiliatedAuthorKim, Ho Seong-
dc.contributor.affiliatedAuthorHan, Song Yi-
dc.contributor.affiliatedAuthorKim, Kyu Yeun-
dc.citation.titleYonsei Medical Journal-
dc.citation.volume58-
dc.citation.number1-
dc.citation.startPage174-
dc.citation.endPage179-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.58(1) : 174-179, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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