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Lenticulostriate Artery Involvement is Predictive of Poor Outcomes in Superficial Middle Cerebral Artery Territory Infarctio

DC FieldValueLanguage
dc.contributor.author김영대-
dc.contributor.author김은혜-
dc.contributor.author남효석-
dc.contributor.author송동범-
dc.contributor.author이기정-
dc.contributor.author이혜선-
dc.contributor.author허지회-
dc.date.accessioned2017-11-02T08:10:12Z-
dc.date.available2017-11-02T08:10:12Z-
dc.date.issued2017-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154158-
dc.description.abstractPURPOSE: Patients with superficial middle cerebral artery (MCA) territory infarction may have concomitant lenticulostriate artery (LSA) territory infarction. We investigated the mechanisms thereof and the outcomes of patients with superficial MCA territory infarction according to the presence or absence of LSA involvement. MATERIALS AND METHODS: Consecutive patients with first-ever infarction in the unilateral superficial MCA territory were included in this study. They were divided into the superficial MCA only (SM) group and the superficial MCA plus LSA (SM+L) group. RESULTS: Of the 398 patients, 84 patients (21.1%) had LSA involvement (SM+L group). The SM+L group more frequently had significant stenosis of the proximal MCA or carotid artery and high-risk cardioembolic sources. Stroke severity and outcomes were remarkably different between the groups. The SM+L group showed more severe neurologic deficits (National Institute of Health Stroke Scale score 10.8±7.1 vs. 4.0±5.0, p<0.001) and larger infarct in the superficial MCA territory (40.8±62.6 cm³ vs. 10.8±21.8 cm³, p<0.001) than the SM group. A poor functional outcome (mRS >2) at 3 months was more common in the SM+L group (64.3% vs. 15.9%, p<0.001). During a mean follow-up of 26 months, 67 patients died. All-cause (hazard ratio, 2.246) and stroke (hazard ratio, 9.193) mortalities were higher in the SM+L group than the SM group. In multivariate analyses, LSA involvement was an independent predictor of poor functional outcomes and stroke mortality. CONCLUSION: LSA territory involvement is predictive of poor long-term outcomes in patients with superficial MCA territory infarction.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCarotid Stenosis/mortality-
dc.subject.MESHCarotid Stenosis/pathology-
dc.subject.MESHConstriction, Pathologic/pathology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfarction, Middle Cerebral Artery/mortality-
dc.subject.MESHInfarction, Middle Cerebral Artery/pathology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Cerebral Artery/pathology*-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHStroke/mortality-
dc.subject.MESHStroke/pathology-
dc.titleLenticulostriate Artery Involvement is Predictive of Poor Outcomes in Superficial Middle Cerebral Artery Territory Infarctio-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Neurology-
dc.contributor.googleauthorKijeong Lee-
dc.contributor.googleauthorEun Hye Kim-
dc.contributor.googleauthorDongbeom Song-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorJi Hoe Heo-
dc.identifier.doi10.3349/ymj.2017.58.1.123-
dc.contributor.localIdA00828-
dc.contributor.localIdA01273-
dc.contributor.localIdA02017-
dc.contributor.localIdA02696-
dc.contributor.localIdA03312-
dc.contributor.localIdA04369-
dc.contributor.localIdA00702-
dc.relation.journalcodeJ02813-
dc.identifier.pmid27873504-
dc.subject.keywordLenticulostriate artery-
dc.subject.keywordcerebral infarction-
dc.subject.keywordmiddle cerebral artery-
dc.subject.keywordmortality-
dc.subject.keywordprognosis-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.alternativeNameKim, Eun Hye-
dc.contributor.alternativeNameNam, Hyo Suk-
dc.contributor.alternativeNameSong, Dong Beom-
dc.contributor.alternativeNameLee, Ki Jeong-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Eun Hye-
dc.contributor.affiliatedAuthorNam, Hyo Suk-
dc.contributor.affiliatedAuthorSong, Dong Beom-
dc.contributor.affiliatedAuthorLee, Ki Jeong-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Young Dae-
dc.citation.titleYonsei Medical Journal-
dc.citation.volume58-
dc.citation.number1-
dc.citation.startPage123-
dc.citation.endPage130-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.58(1) : 123-130, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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