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폐경 후 여성에서 흡연이 골다공증성 척추 골절에 미치는 영향

Other Titles
 Effect of Smoking on Osteoporotic Vertebral Fracture in Postmenopausal Women 
Authors
 Sang-Pil Yoon  ;  Seung-Hwan Lee  ;  Byeong-Mun Park  ;  Kyung-Sub Song  ;  Geun Jang  ;  Beom-Seok Lee  ;  Hwan-Mo Lee  ;  Seong-Hwan Moon 
Citation
 Journal of Korean Society of Spine Surgery, Vol.23(1) : 1-6, 2016 
Journal Title
 Journal of Korean Society of Spine Surgery 
ISSN
 2093-4378 
Issue Date
2016
Abstract
Study Design : A retrospective study. Objectives : To evaluate the association between smoking and osteoporotic vertebral fractures (OVFs) in postmenopausal women. Summary of Literature Review : Several studies have examined the relationship of smoking with hip fractures, but few studies have analyzed the relationship of smoking with spine fractures in women thus far. Materials and Methods : This study considered 1255 postmenopausal women aged 50 years and older (enrollment from April 2008 to January 2009) from 62 study sites in a nationwide hospital. The amount of smoking was calculated in pack-years. Further, OVFs were diagnosed using a semi-quantitative method. To analyze the relationship between smoking and OVFs, we used a paired t-test, a χ2-test, and a binary logistic regression analysis. Results : The past history of smoking was 7.2% in the patient group and 4.3% in the control group (p=0.025). The mean pack-years of smoking was 0.34 in the control group and 0.62 in the patient group (p=130). The mean T-score in the lumbar bone mass density (BMD) was ?1.64 in the control group and ?2.19 in the patient group (p=0.409). Smoking was a risk factor of vertebral fractures in postmenopausal women (odd's ratio=1.68, 95% confidence interval=1.020?2.759, p=0.042) irrespective of the lumbar BMD and the medical treatment for osteoporosis and obesity. Conclusions : Smoking is a risk factor for osteoporotic vertebral fractures in postmenopausal women independently without regard to lumbar BMD. Therefore, cessation of smoking is important for the prevention of OVFs in postmenopausal women.
Files in This Item:
T201606085.pdf Download
DOI
10.4184/jkss.2016.23.1.1
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Seong Hwan(문성환)
Lee, Hwan Mo(이환모) ORCID logo https://orcid.org/0000-0002-5405-3832
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/153084
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