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Physical Activity Level and Colorectal Cancer Mortality

Authors
 Yejin Mok  ;  Christina Jeon  ;  Gyu Jang Lee  ;  Sun Ha Jee 
Citation
 ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH, Vol.28(7) : 638-647, 2016 
Journal Title
ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH
ISSN
 1010-5395 
Issue Date
2016
MeSH
Adult ; Colorectal Neoplasms/mortality* ; Exercise* ; Female ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Prospective Studies ; Republic of Korea/epidemiology ; Risk
Keywords
cohort study ; colorectal cancer ; epidemiology ; metabolic equivalent of task ; physical activity
Abstract
Physical activity has been shown to reduce colorectal cancer risk. However, the association of physical activity levels separately with colon and rectum cancer mortality is less clear. We included 226?089 Korean in a large prospective cohort study. We assessed the associations of physical activity levels (length, frequency, and intensity) with colon and rectum cancer mortality using Cox proportional hazards model. Men, but not women, who had regular physical activity showed a lower risk of death from colon cancer. The association for high intensity of physical activity was borderline significant in men (hazard ratio 0.67; 95% CI = 0.45-1.00 for >17.5 MET-hour/week). The associations were largely consistent among those aged <55 years, body mass index <25 kg/m2, low high-density lipoprotein cholesterol, current smoker, and without hypertension or history of cardiovascular disease. In conclusion, higher length or intensity of physical activity decreased colon, but not rectum cancer mortality in men. Regular physical activity may have beneficial effects on colon cancer survival.
Full Text
http://journals.sagepub.com/doi/abs/10.1177/1010539516661761
DOI
10.1177/1010539516661761
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/153052
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