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Elective neck dissection versus observation in early stage oral squamous cell carcinoma: recurrence and survival

 Dong Wook Kim  ;  Ba-Da Lee  ;  Jung Hwan Lim  ;  Jung-Hyun Park  ;  Woong Nam  ;  Hyung Jun Kim  ;  In-Ho Cha 
 Journal of the Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회지), Vol.42(6) : 358-364, 2016 
Journal Title
 Journal of the Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회지) 
Issue Date
OBJECTIVES: To evaluate the results of elective neck dissection versus those of observation in the treatment of early stage oral squamous cell carcinoma and to identify factors related to recurrence and survival. MATERIALS AND METHODS: This was a retrospective study of 52 patients who underwent elective neck dissection and 27 who did not receive neck dissection. RESULTS: In survival analyses, elective neck dissection showed a benefit in overall recurrence (P=0.027), especially in stage I patients (P=0.024). With regard to survival, the benefit was statistically insignificant (P=0.990). In multivariable analysis, overall recurrence was independently related to poor histologic grade (odds ratio [OR]=9.65, P=0.006), and cancer-specific death was independently related to advanced age (OR=6.3, P=0.022), higher clinical T stage (OR=15.2, P=0.01), and poorly differentiated histologic grade (OR=6.6, P=0.025). CONCLUSION: Though there was lower recurrence in the elective neck dissection group, there were no statistically significant results on survival. The characteristics of the tumor itself, such as clinical T stage and poor histologic grade, may be more important in cancer-specific survival.
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2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyung Jun(김형준) ORCID logo https://orcid.org/0000-0001-8247-4004
Nam, Woong(남웅) ORCID logo https://orcid.org/0000-0003-0146-3624
Lim, Jung Hwan(임정환)
Cha, In Ho(차인호) ORCID logo https://orcid.org/0000-0001-8259-2190
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