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심혈관질환 예방을 위한 고정용량 복합제 치료

Other Titles
 Fixed-dose combination therapy for cardiovascular prevention 
Authors
 이상학 
Citation
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION , Vol.59(11) : 883-887, 2016 
Journal Title
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION 
ISSN
 1975-8456 
Issue Date
2016
Abstract
n patients with high cardiovascular risk, the number of drugs needed is often high, and this may decrease long-term adherence. Therefore, maintaining good adherence and reducing cardiovascular risk is currently an important issue in preventive cardiology. The combination of two different antihypertensive agents is reported to reduce blood pressure more than the doubling of a single agent. In addition, the prevalence of adverse events with two drugs is less than the sum of the number of events associated with each drug. The combination of renin-angiotensin system blockers with statins is a widely used regimen in cardiovascular prevention. Recent clinical trials using a fixed-dose combination of aspirin, statins, and angiotensin-converting enzyme inhibitors has revealed better adherence in the combination group than in the group with separately administered drugs. Interestingly, this benefit was more prominent in patients who were under-treated (less adherent) at baseline.
Files in This Item:
T201604879.pdf Download
DOI
10.5124/jkma.2016.59.11.883
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Sang Hak(이상학) ORCID logo https://orcid.org/0000-0002-4535-3745
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152598
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